Tango Therapeutics is the lead sponsor of 4 current clinical trials in our USA register. 3 are recruiting patients now. All registered phases are Phase 1/2. The drugs named most often in its trials are Pembrolizumab, TNG462 and Abemaciclib. The most-studied condition is Non Small Cell Lung Cancer.
| Study | Phase | Status | Start | Registers |
|---|---|---|---|---|
|
Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
NCT06922591 · PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, NSCLC
|
Phase 1/2 | Recruiting | 2025-05 | USA |
|
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
NCT06810544 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer, Glioma Glioblastoma Multiforme, Glioma, Malignant
Drug: Abemaciclib |
Phase 1/2 | Recruiting | 2025-03 | USA |
|
Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
NCT05732831 · ClinicalTrials.gov ↗ · Locally Advanced Solid Tumor
Drugs: Pembrolizumab, TNG462 |
Phase 1/2 | Recruiting | 2023-05 | USA |
|
Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors
NCT05887492 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer, Solid Tumors, Adult, Lung Cancer
Drug: Pembrolizumab |
Phase 1/2 | Active, closed | 2023-06 | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.
Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 4 | 3 |
A trial with sites in more than one country appears in each of those registers.
Sponsors with the most current trials registered for this condition.
Tango Therapeutics is the lead sponsor of 4 current trials on ClinicalTrials.gov in our USA register, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Yes. 3 of its 4 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Its current trials name 7 drugs and biologicals as interventions. The most frequent are Pembrolizumab (2), TNG462 (2), Abemaciclib (1), Gemcitabine/nab-paclitaxel (1) and MFOLFIRINOX (1). The number in brackets is how many of its trials name each drug.
Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.
Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.