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Nuvation Bio clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine and the EU Clinical Trials Information System (CTIS) — current trials in our USA, China, Canada, France, Spain, Italy, Poland, Japan, South Korea, Australia and EU (CTIS) registers with Nuvation Bio as lead sponsor. Synced 27 Sep 2026
8Current trials
3Recruiting now
3Drugs in these trials
11Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Nuvation Bio is the lead sponsor of 8 current clinical trials in our USA, China, Canada, France, Spain, Italy, Poland, Japan, South Korea, Australia and EU (CTIS) registers. 3 are recruiting patients now. The most common phase is Phase 3. The drugs named most often in its trials are Taletrectinib, Safusidenib and Crizotinib. The most-studied condition is Non Small Cell Lung Cancer.

ClinicalTrials.gov trials by status

  • Recruiting343%
  • Not yet open114%
  • Active, closed343%

Trials by phase

  • Phase 3343%
  • Phase 2343%
  • Phase 1/2114%
01

Clinical trials sponsored by Nuvation Bio

7 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)
NCT07154706 · Non-small Cell Lung Cancer (NSCLC)
Phase 3 Recruiting 2025-08 USA, China, Canada
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
NCT05303519 · ClinicalTrials.gov ↗ · Glioma, Astrocytoma, Grade IV, IDH1-mutant Glioma
Phase 3 Recruiting 2023-06 USA, China, Australia
A Phase III Study Comparing Taletrectinib With Standard Therapy in ROS1 Positive Locally Advanced or Metastatic Non-small Cell Lung Cancer Patients
NCT06564324 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer
Phase 3 Recruiting 2024-11 China
Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease
NCT07703436 · ClinicalTrials.gov ↗ · Grade 2 IDH1-mutant Glioma, Grade 3 IDH1-mutant Glioma, Glioma
Phase 2 Not yet open 2027-03 USA
Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC
NCT04919811 · Non Small Cell Lung Cancer
Phase 2 Active, closed 2021-09 USA, China, France, Spain, Italy, Poland, Canada, Japan, South Korea
A Study of AB-106 in Subjects With Advanced NSCLC Harboring ROS1 Fusion Gene
NCT04395677 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer
Phase 2 Active, closed 2020-07 China
Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors
NCT06334432 · ClinicalTrials.gov ↗ · Advanced Solid Tumor, HER2-negative Breast Cancer, Metastatic Castration-resistant Prostate Cancer (mCRPC)
Phase 1/2 Active, closed 2024-03 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Nuvation Bio in the EU trials register (CTIS)

1 trial

Authorised or ongoing trials in the EU Clinical Trials Information System with Nuvation Bio as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.

StudyPhaseStatusCountries
A Phase 3 Multicenter Double-blind Randomized Study of Taletrectinib Versus Placebo in Patients With ROS1-Fusion Positive Stage IB-IIIA Non-Small Cell Lung Cancer Who Have Undergone Complete Tumor Resection
2025-521971-29-00 · CTIS ↗ · Respiratory Tract Diseases
Phase 3 Authorised Spain, Belgium, France + 2 more
03

Drugs in Nuvation Bio trials

3 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

04

Conditions in Nuvation Bio trials

12 conditions
Non Small Cell Lung Cancer3Glioma2IDH1-mutant Glioma2Non-small Cell Lung Cancer (NSCLC)1Astrocytoma, Grade IV1Astrocytoma, IDH-Mutant, Grade 31Grade 2 IDH1-mutant Glioma1Grade 3 IDH1-mutant Glioma1Advanced Solid Tumor1HER2-negative Breast Cancer1Metastatic Castration-resistant Prostate Cancer (mCRPC)1Pancreatic Cancer1
05

By trial register

RegisterTrialsRecruiting
Clinical trials in USA52
Clinical trials in China53
Clinical trials in Canada21
Clinical trials in France10
Clinical trials in Spain10
Clinical trials in Italy10
Clinical trials in Poland10
Clinical trials in Japan10
Clinical trials in South Korea10
Clinical trials in Australia11
EU register (CTIS)1—

A trial with sites in more than one country appears in each of those registers.

06

Other sponsors in Non Small Cell Lung Cancer

SponsorTrials
Hunan Province Tumor Hospital10
MediLink Therapeutics (Suzhou)4
Shanghai Henlius Biotech4
Peking Union Medical College Hospital4
Intergroupe Francophone de Cancerologie Thoracique4
Fundación GECP4
Guangdong Association of Clinical Trials3
Verastem2
ETOP IBCSG Partners Foundation2
OncoC42

Sponsors with the most current trials registered for this condition.

07

Questions about Nuvation Bio trials

How many clinical trials does Nuvation Bio sponsor?

Nuvation Bio is the lead sponsor of 7 current trials on ClinicalTrials.gov in our USA, China, Canada, France, Spain, Italy, Poland, Japan, South Korea and Australia registers, and 1 authorised or ongoing trial in the EU register (CTIS), as of the registry sync on 27 September 2026. Completed and withdrawn studies are not counted.

Are Nuvation Bio trials recruiting?

Yes. 3 of its 7 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Nuvation Bio testing?

Its current trials name 3 drugs and biologicals as interventions. The most frequent are Taletrectinib (5), Safusidenib (2) and Crizotinib (1). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 27 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.