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Compound · clinical trials

IBI310 clinical trials

Also listed in trial records as Ipilimumab N01, CTLA-4 Antibody
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 10 trials in our China register that name IBI310 as an intervention. Synced 26 Sep 2026
10Current trials
7Recruiting now
7Lead sponsors
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

IBI310 is named as an intervention in 10 current clinical trials in our China register. 7 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Tianjin Medical University Cancer Institute and Hospital (2). The most-studied condition is Hepatocellular Carcinoma (HCC).

Trials by status

  • Recruiting770%
  • Not yet open220%
  • Active, closed110%

Trials by phase

  • Phase 2880%
  • Phase 2/3220%
01

Clinical trials of IBI310

10 trials
StudyPhaseStatusLead sponsorRegisters
A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment.
NCT07490262 · ClinicalTrials.gov ↗ · Hepatocellular Carcinoma (HCC)
Phase 2/3 Recruiting Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD China
Neoadjuvant and Adjuvant Therapy Studies of Sintilimab Combined With Chemotherapy With or Without Ipilimumab N01 in Resectable Gastric/Gastroesophageal Junction Adenocarcinoma
NCT07643623 · ClinicalTrials.gov ↗ · Resectable Gastric/Gastroesophageal Junction Adenocarcinoma
Phase 2/3 Recruiting Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD China
Sintilimab Combined With IBI310 and Surufatinib for the Treatment of G3-NET and NEC (NESSIE)
NCT05165407 · ClinicalTrials.gov ↗ · Neuroendocrine Neoplasm
Phase 2 Recruiting Peking University China
Efficacy of Anti-CTLA-4 Antibody Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Resectable Stage II-III Non-Small Cell Lung Cancer
NCT07410975 · ClinicalTrials.gov ↗ · NSCLC Stage II, NSCLC Stage III
Phase 2 Recruiting Shanghai Pulmonary Hospital, Shanghai, China China
A Prospective, Randomized Study of TACE Combined With Sintilimab, Bevacizumab, and Ipilimumab N01 Treating Advanced HCC
NCT07422753 · ClinicalTrials.gov ↗ · Hepatocellular Carcinoma (HCC)
Phase 2 Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine China
A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer
NCT07506109 · ClinicalTrials.gov ↗ · BRAF V600E, Colorectal Cancer, Sintilimab
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
Ipilimumab N01 Combined With Sintilimab, Bevacizumab Biosimilar, and Hepatic Arterial Infusion Chemotherapy as Conversion Therapy for Unresectable Intermediate-Advanced Hepatocellular Carcinoma
NCT07560488 · ClinicalTrials.gov ↗ · HCC - Hepatocellular Carcinoma, Conversion Therapy
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
Efficacy of PD-1 Inhibitor Combination Therapy in Non-small Cell Lung Cancer Patients Who Have Not Achieved Major Pathologic Response After Neoadjuvant Immunotherapy: a Multicenter, Phase II Clinical Trial
NCT06620822 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer
Phase 2 Not yet open Shanghai Pulmonary Hospital, Shanghai, China China
SBRT Followed by Ipilimumab N01, Sintilimab, Nab-Paclitaxel and Gemcitabine for Locally Advanced Pancreatic Cancer
NCT07683221 · ClinicalTrials.gov ↗ · Pancreatic Cancer
Phase 2 Not yet open Shandong Cancer Hospital and Institute China
PD-L1 Antibody Combined With CTLA-4 Antibody for Patients With Advanced Intrahepatic Cholangiocarcinoma Who Progressed After Standard Treatment
NCT04634058 · ClinicalTrials.gov ↗ · Cholangiocarcinoma, Intrahepatic, PD-L1, CTLA4
Phase 2 Active, closed Shanghai Zhongshan Hospital China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with IBI310

16 conditions
Hepatocellular Carcinoma (HCC)2BRAF V600E1Colorectal Cancer1Sintilimab1MSS (Microsatellite Stable)1Resectable Gastric/Gastroesophageal Junction Adenocarcinoma1Pancreatic Cancer1HCC - Hepatocellular Carcinoma1Conversion Therapy1Cholangiocarcinoma, Intrahepatic1PD-L11CTLA41
All 16 conditions
Condition (as registered)Trials
Hepatocellular Carcinoma (HCC)2
BRAF V600E1
Colorectal Cancer1
Sintilimab1
MSS (Microsatellite Stable)1
Resectable Gastric/Gastroesophageal Junction Adenocarcinoma1
Pancreatic Cancer1
HCC - Hepatocellular Carcinoma1
Conversion Therapy1
Cholangiocarcinoma, Intrahepatic1
PD-L11
CTLA41
NSCLC Stage II1
NSCLC Stage III1
Non Small Cell Lung Cancer1
Neuroendocrine Neoplasm1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Tianjin Medical University Cancer Institute and Hospital2
Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD2
Shanghai Pulmonary Hospital, Shanghai, China2
Second Affiliated Hospital, Zhejiang University, School of Medicine1
Shandong Cancer Hospital and Institute1
Shanghai Zhongshan Hospital1
Peking University1
04

By country register

RegisterTrialsRecruiting
Clinical trials in China107

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about IBI310 trials

How many clinical trials are testing IBI310?

10 current trials in our China register name IBI310 (also registered as Ipilimumab N01) as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are IBI310 trials recruiting patients?

Yes. 7 of the 10 trials are recruiting: 7 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors IBI310 clinical trials?

Tianjin Medical University Cancer Institute and Hospital (2), Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD (2), Shanghai Pulmonary Hospital, Shanghai, China (2) and Second Affiliated Hospital, Zhejiang University, School of Medicine (1), among 7 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how IBI310 works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how IBI310 works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists IBI310 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.