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Clinical Trials in Turkey / NCT07726251
Recruiting Observational

Hemodynamic Changes and Trigeminocardiac Reflex During Bimaxillary Orthognathic Surgery

NCT07726251 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2026-06-20
Last updated
2026-07-28

Condition(s) studied

Orthognathic SurgeryTrigeminocardiac ReflexHemodynamic

Study summary

This observational study aims to evaluate hemodynamic changes occurring during bimaxillary orthognathic surgery using routinely collected intraoperative monitoring data. Heart rate, systolic and diastolic blood pressure, mean arterial pressure, and oxygen saturation will be recorded during different stages of surgery as part of standard clinical care.

The study will also evaluate the occurrence of the trigeminocardiac reflex (TCR) and its association with patient characteristics and surgical stages. No additional interventions, laboratory tests, or procedures will be performed beyond routine clinical practice. The findings may contribute to the early recognition and management of intraoperative hemodynamic changes during orthognathic surgery.

Eligibility

Sex
ALL
Min age
18 Years
Max age
40 Years
Healthy volunteers
No
Inclusion Criteria: * Adults aged 18-40 years. * Patients with an indication for bimaxillary orthognathic surgery. * Patients with complete routine intraoperative hemodynamic monitoring data. * Patients who provide written informed consent to participate in the study. Exclusion Criteria: * Patients without an indication for bimaxillary orthognathic surgery. * Individuals younger than 18 years or older than 40 years. * Patients with known cardiovascular disease, including arrhythmia, heart failure, coronary artery disease, or other significant cardiovascular disorders. * Patients with systemic diseases, including diabetes mellitus, hypertension, thyroid disorders, or other significant systemic conditions. * Patients with diagnosed psychiatric disorders. * Patients with incomplete or irregularly recorded intraoperative hemodynamic monitoring data. * Individuals who refuse to participate or do not provide written informed consent.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Kırıkkale Univesity Faculty of Dentistry Kirikkale Kırıkkale Recruiting

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Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07726251 on ClinicalTrials.gov ↗ ← All trials in Turkey