Chronic Total Occlusion and Triglyceride-Glucose Index

NCT07451860 · tracked via the Priya Life Science Turkey tracker

Sponsor

Kırıkkale University

Phase

Observational

Started

2026-03-15

Last updated

2026-03-05

Condition(s) studied

CAD - Coronary Artery DiseaseChronic Total Occlusion (CTO)Triglycerid Glucose Index

Investigational drug(s) / intervention(s)

triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2.

triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2.: As no previous studies have demonstrated the predictive value of the TyG index for chronic total occlusion (CTO), the present investigation provides a novel contribution to the literature. We hypothesize that the triglyceride-glucose (TyG) index will be significantly higher in patients with chronic total occlusion (CTO) compared to those without CTO.

Study summary

We retrospectively analyzed 200 CAD patients undergoing coronary angiography between 2026-2027. Patients were grouped by CTO presence. Clinical and laboratory parameters were compared, and logistic regression was performed to identify independent predictors.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Accepted

Inclusion Criteria: * Adults ≥18 years of age, patients undergoing coronary angiography, non-obese individuals Exclusion Criteria: * Patients \<18 years of age, history of atrial fibrillation, pacemaker implantation, asthma, pulmonary hypertension, pregnancy, anemia, malignancy, rheumatoid arthritis, or peripheral artery disease, obesity (BMI \>30 kg/m²), inaccessible patient records

Primary outcome measure(s)

The primary outcome measure will be the difference in the triglyceride-glucose (TyG) index between patients with chronic total occlusion (CTO) and those without CTO, assessed from routinely obtained blood samples. — 1 Year

Trial sites (1)

Facility	City	Region	Status
Kırıkkale university	Kirikkale	Turkey (Türkiye)

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Other trials for the same condition

Turkish Chronic Total Occlusion Percutaneous Coronary Intervention Registry Starting soon

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07451860 on ClinicalTrials.gov ↗ ← All trials in Turkey