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Clinical Trials in Turkey / NCT07639489
Starting soon Observational

Mechanical Power and Pulmonary Complications in CABG Surgery

NCT07639489 · tracked via the Priya Life Science Turkey tracker
Sponsor
Fusun Gozen
Phase
Observational
Started
2026-06
Last updated
2026-06-10

Condition(s) studied

Postoperative Pulmonary ComplicationsCoronary Artery Bypass Graft Surgery (CABG)Prolonged Mechanical Ventilation

Investigational drug(s) / intervention(s)

Intraoperative Mechanical Ventilation Monitoring

Intraoperative Mechanical Ventilation Monitoring: Intraoperative ventilatory parameters (tidal volume, respiratory rate, plateau pressure, PEEP) are routinely recorded during CABG surgery. Mechanical power and driving pressure are calculated from these parameters. No additional intervention is applied beyond standard clinical care.

Study summary

This prospective observational study evaluates the association between intraoperative mechanical power (MP) - a composite measure of the total energy delivered to the lungs during mechanical ventilation - and postoperative pulmonary complications (PPCs) and prolonged mechanical ventilation in adult patients undergoing elective coronary artery bypass graft (CABG) surgery with cardiopulmonary bypass (CPB). Intraoperative ventilatory parameters including tidal volume, respiratory rate, airway pressures, and PEEP will be recorded and used to calculate MP and driving pressure (DP). No additional interventions will be applied beyond standard clinical care.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age 18 years or older * Scheduled for elective, first-time isolated CABG surgery * Use of cardiopulmonary bypass (CPB) * Intraoperative mechanical ventilation applied under general anesthesia with recordable ventilator data * Provision of written informed consent Exclusion Criteria: * Emergency cardiac surgery * Off-pump CABG (without CPB) * Preoperative requirement for invasive mechanical ventilation * Advanced chronic lung disease * Incomplete or unreliable intraoperative ventilatory data * Intraoperative use of advanced non-standard support (ECMO)

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Türkiye Bursa Turkey (Türkiye)

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07639489 on ClinicalTrials.gov ↗ ← All trials in Turkey