Systemic Inflammatory Markers In Vocal Cord Lesions

NCT07626125 · tracked via the Priya Life Science Turkey tracker

Sponsor

Antalya Health Sciences University

Phase

Observational

Started

2026-05-22

Last updated

2026-06-09

Condition(s) studied

Laryngeal LesionsSystemic Inflammatory Process

Investigational drug(s) / intervention(s)

Laryngeal polypsLaryngeal nodulesLaryngeal cystsReinke's edemaPapillomasDysplasiaHigh-risk premalignant lesionsMalignant vocal cord lesionsAsymptomatic smokers without vocal cord lesions

Laryngeal polyps: Bening laryngeal lesions

Laryngeal nodules: Bening laryngeal lesions

Laryngeal cysts: Bening laryngeal lesions

Reinke's edema: Bening laryngeal lesions

Papillomas: Premalign laryngeal lesions

Dysplasia: Premalign laryngeal lesions

High-risk premalignant lesions: Premalign laryngeal lesions

Malignant vocal cord lesions: Malign laryngeal lesions

Asymptomatic smokers without vocal cord lesions: None laryngeal lesions

Study summary

The aim of this study is to evaluate the levels of systemic inflammatory markers such as PIV, SII, and NPAR in patients with benign and premalignant laryngeal lesions and to determine the diagnostic accuracy of these values using ROC analysis.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Patients aged 18 years and older * Patients with a diagnosis of vocal cord lesion via endoscopic or surgical means * Patients with complete blood count and albumin data in their hospital records Exclusion Criteria: * Acute infection * Autoimmune disease * Other malignancy * Steroid use * Hematological disease * Systemic inflammatory disease * Missing laboratory data

Primary outcome measure(s)

Determining the diagnostic accuracy of PIV — Postoperative 1 month
PIV (pan-immune-inflammation value)

Trial sites (1)

Facility	City	Region	Status
University of Health Sciences, Antalya Training and Research Hospital	Antalya	Muratpaşa

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07626125 on ClinicalTrials.gov ↗ ← All trials in Turkey