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Clinical Trials in Turkey / NCT07539467
Enrolling by invitation Not applicable

"The Effect of Adductor Canal Block Performed With Postoperative Thigh Tourniquet Application on Pain After Total Knee Arthroplasty"

NCT07539467 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2026-03-01
Last updated
2026-04-20

Condition(s) studied

Total Knee Arthroplasty for Gonarthrosis

Investigational drug(s) / intervention(s)

Tourniquet-Assisted Adductor Canal Block (T-ACB) grouStandard Adductor Canal Block (S-ACB)

Tourniquet-Assisted Adductor Canal Block (T-ACB) grou: Participants received an ultrasound-guided distal adductor canal block. The procedure was performed in two stages: First, a pneumatic tourniquet placed on the proximal thigh was inflated for 3-5 minutes (at a pressure of approximately 142-202 mmHg), during which 20 mL of 0.25% bupivacaine was injected. Subsequently, the tourniquet was deflated, and an additional 20 mL of 0.25% bupivacaine was administered, reaching a total volume of 40 mL. This technique aimed to enhance the distribution of the local anesthetic through the adductor hiatus to the popliteal plexus at the posterior aspect of the knee.

Standard Adductor Canal Block (S-ACB): Participants received a standard ultrasound-guided distal adductor canal block. During the procedure, 20 mL of 0.25% bupivacaine was injected in a single dose without any tourniquet modification or additional pressure application. The technique relied on the natural, passive, and anatomical distribution of the local anesthetic within the adductor canal.

Study summary

The biggest fear for patients undergoing knee replacement surgery is that persistent pain felt at the back of the knee postoperatively. While regional anesthesia is generally successful at numbing the front of the knee, managing pain in the posterior (back) area is not always easy. In this study, we tested a new method designed to alleviate pain in the back of the knee and improve patient comfort.

Eligibility

Sex
ALL
Min age
40 Years
Max age
85 Years
Healthy volunteers
No
Inclusion Criteria Patients aged 40-85 years, with a BMI of 18-35 kg/m², and an ASA physical status of I-III who underwent total knee arthroplasty (TKA) under spinal anesthesia were included. Eligible participants were those who volunteered to participate and provided written informed consent. Exclusion Criteria To ensure methodological standardization, the following cases were excluded: Patients undergoing revision surgery. Those undergoing unicompartmental (unicondylar) knee replacement, as the severity of surgical trauma differs from total replacement. Bilateral cases, to prevent potential bias in assessing postoperative opioid consumption and pain scores. Additionally, patients were excluded if: The surgical duration exceeded 180 minutes. There was a known history of coagulopathy, peripheral neuropathy, or allergy to local anesthetics. The spinal anesthesia was insufficient, requiring a conversion to general anesthesia.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Ankara Etlik Şehir Hastanesi Ankara Turkey (Türkiye)

More Ankara Etlik City Hospital trials in Turkey

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07539467 on ClinicalTrials.gov ↗ ← All trials in Turkey