Laparoscopic appendectomy with 10 mmHg pneumoperitoneumLaparoscopic appendectomy with 15 mmHg pneumoperitoneum
Laparoscopic appendectomy with 10 mmHg pneumoperitoneum: Laparoscopic appendectomy performed using an intra-abdominal pneumoperitoneum pressure of 10 mmHg.
Laparoscopic appendectomy with 15 mmHg pneumoperitoneum: Laparoscopic appendectomy performed using an intra-abdominal pneumoperitoneum pressure of 15 mmHg.
Study summary
This prospective, randomized controlled trial aims to compare the clinical outcomes of laparoscopic appendectomy performed under two standard pneumoperitoneum pressures (10 mmHg and 15 mmHg). The primary objective is to evaluate postoperative pain, while secondary outcomes include operative time, conversion rate, time to first flatus and bowel movement, length of hospital stay, postoperative ileus, and intra-abdominal abscess formation. The study will determine whether lower-pressure pneumoperitoneum provides comparable surgical conditions while improving postoperative recovery.
Eligibility
Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria:
* Age 18-60 years.
* Clinical and/or radiological diagnosis of acute appendicitis.
* Planned laparoscopic appendectomy(Uncomplicated acute appendicitis considered suitable for laparoscopic management).
* ASA physical status I-III.
* Written informed consent.
Exclusion Criteria:
* Age \<18 years and \>60 years
* Pregnancy
* Appendiceal mass or suspected appendiceal malignancy
* Diffuse peritonitis requiring planned open surgery
* Severe cardiopulmonary disease in whom pneumoperitoneum pressure cannot be standardized
* Previous extensive abdominal surgery causing expected severe adhesions
* Patients requiring additional major abdominal procedure
* Missing consent
* Incomplete postoperative follow-up
* Patients managed non-operatively without surgery
Primary outcome measure(s)
Postoperative pain (Numeric Rating Scale [NRS] 0-10) — At 6 and 24 hours postoperatively Postoperative pain will be assessed using the 11-point Numeric Rating Scale (NRS; 0 = no pain, 10 = worst imaginable pain). Pain scores will be compared between the 10 mmHg and 15 mmHg pneumoperitoneum groups.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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