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Clinical Trials in Turkey / NCT07493213
Recruiting Not applicable

USG-Guided Shoulder Injections in Frozen Shoulder

NCT07493213 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2026-04-01
Last updated
2026-05-14

Condition(s) studied

Frozen ShoulderAdhesive CapsulitisShoulder PainNociplastic PainNeuropathic Pain

Investigational drug(s) / intervention(s)

USG-guided suprascapular nerve blockUSG-Guided suprascapular nerve block plus subacromial injection.

USG-guided suprascapular nerve block: USG-guided suprascapular nerve block + home-based exercises

USG-Guided suprascapular nerve block plus subacromial injection.: USG-Guided suprascapular nerve block plus subacromial injection + home-based exercises

Study summary

Frozen shoulder (adhesive capsulitis) is characterized by pain and a progressive restriction of both active and passive shoulder range of motion, significantly impairing daily activities and quality of life. This study aims to evaluate the effectiveness of USG-guided shoulder injections, when added to a home-based exercise program, in the conservative management of patients with chronic, painful frozen shoulder.

In this prospective randomized study, patients diagnosed with painful frozen shoulder will be included. In addition to a standardized home-based exercise program, patients will receive either USG-guided suprascapular nerve block alone or a combination of suprascapular nerve block and subacromial injection. The effects of these approaches on clinical outcomes will be assessed over a 20-week follow-up period.

Primary outcome measures include pain intensity assessed by the Visual Analog Scale (VAS), functional status evaluated by the Shoulder Pain and Disability Index (SPADI), and shoulder range of motion. Secondary outcomes include depression level (Beck Depression Inventory), sleep quality, pain phenotype (nociplastic, neuropathic, or nociceptive), hand grip strength, ultrasonographic findings ( (coracohumeral ligament thickness, subacromial bursa thickness) , and patient satisfaction (subjective impression of improvement).

The results of this study are expected to provide evidence on the comparative effectiveness and additional benefits of different shoulder injection approaches when combined with home-based exercise therapy in patients with chronic frozen shoulder.

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: Age between 18 and 75 years and willingness to participate in the study Presence of shoulder pain lasting at least 3 months and a diagnosis of primary frozen shoulder Pain intensity ≥ 4/10 on the Visual Analog Scale (VAS), resistant to medical treatment/analgesics Restriction of ≥30 degrees in at least two planes of shoulder motion (flexion, abduction, or external rotation) \- Exclusion Criteria: * History of shoulder trauma Presence of neurological conditions such as stroke, brachial plexus injury, Parkinson's disease, or cervical spine pathology with or without radiculopathy History of shoulder surgery, shoulder malignancy or tumor, or prior shoulder manipulation Presence of shoulder arthritis, rotator cuff tear, other shoulder injuries, or thoracic outlet syndrome Systemic diseases affecting the shoulder, severe degeneration or trauma (e.g., osteoarthritis, rheumatoid arthritis, labral or articular cartilage injuries), or inflammatory rheumatic diseases Steroid injection to the affected extremity within the last 3 months, use of oral steroids or NSAIDs, or ongoing surgical/interventional treatment Pregnancy or lactation Uncontrolled diabetes, heart failure, or uncontrolled systemic diseases (e.g., liver failure, chronic kidney disease, significant endocrine disorders) Communication problems or severe psychiatric disorders

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Konya Beyhekim Training and Research Hospital Konya Selçuklu Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07493213 on ClinicalTrials.gov ↗ ← All trials in Turkey