Low-flow anesthesia (LFA) is a technique in which at least 50% of the exhaled air, after carbon dioxide absorption, is mixed with a certain amount of fresh gas and returned to the patient during the next inspiration. In 1974, R. Virtue defined minimal flow anesthesia (MFA) as 0.5 L/min. In 1984, Baker and Simionescu classified LFA as 0.5-1 L/min and MFA as 0.25-0.5 L/min. The aim of this study is to investigate whether there are hemodynamic differences between open-heart surgery cases performed with LFA at different fresh gas flow rates.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
-≥18 years and scheduled for open-heart surgery patients
-ASA I-II-III-IV physical class
Exclusion Criteria:
* Emergency cases
* Patients under 18 years of age
* Patients who have had open heart surgery before
* Patients for whom the use of inhaled anesthetic agents is contraindicated
* Patients who do not sign a voluntary consent form
Primary outcome measure(s)
physiological parameter ; heart rate — Intraoperatively Heart rate will be recorded every 10 minutes, expressed as beats per minute, starting before induction and including the sternotomy and pericardiotomy periods.
physiological parameter; systolic/diastolic blood pressure — Intraoperatively Systolic and diastolic blood pressure will be recorded every 10 minutes in mmHg, starting before induction and including the sternotomy and pericardiotomy periods.
physiological parameter; SpO2 — Intraoperatively SpO2 will be recorded as a percentage every 10 minutes, starting before induction and including the sternotomy and pericardiotomy periods.
Monitoring parameter; Bispectral Index (BIS) — Intraoperatively The BIS value will be recorded numerically every 10 minutes, starting from before induction and including the sternotomy and pericardiotomy periods.
Monitoring parameter; Minimum alveolar concentration (MAC) — Intraoperatively The MAC value will be recorded numerically every 10 minutes, starting from before induction and including the sternotomy and pericardiotomy periods.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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