Analysis of the Gut Microbiota Composition After Consumption of Probiotic Bacteria

Condition(s) studied

Investigational drug(s) / intervention(s)

Consumption of probiotics strain 5: Consumption of probiotic capsules containing the probiotic bacteria Bacillus coagulans strain 5.

Consumption of probiotics strain 6: Consumption of probiotic capsules containing the probiotic bacteria Bacillus coagulans strain 6.

Study summary

The goal of this intervention study is to evaluate the beneficial effect of the probiotic bacterium Bacillus coagulans in healthy volunteers. The main question it aims to answer is if the probiotic strains are modifying the microbiota composition in a beneficial way, evaluated in faecal- and saliva samples.

Primary hypothesis: The probiotic bacteria will modify the microbiota composition in faecal- and saliva samples.

Participants will consume the freeze-dried probiotic bacteria for 14 days. Before and after consumption, the participants will collect samples.

Eligibility

Primary outcome measure(s)

• The gut microbiota composition — At enrollment and after 2 weeks of consumption.
  Diversity index will be calculated based on the results from next generation sequencing

Trial sites (1)

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