BAY 3670549: intravenous (IV) treatment
Placebo: intravenous (IV) treatment
The main goal of this study is to find out how well BAY 3670549 works, how safe it is, how well people can tolerate it, and how the body handles the medicine. The study will compare BAY 3670549 to a placebo (a dummy treatment with no active medicine) in people with AF who need a treatment called electrical cardioversion.
Electrical cardioversion is a procedure that helps the heart return to a normal rhythm. In this study, each participant will get a single intravenous (IV) infusion of either BAY 3670549 or a placebo. Participants will then be observed to see whether the heart rhythm returns to a normal rhythm. If it does not, electrical cardioversion can still be performed as planned. The study will look at how many participants return from AF to a normal rhythm, without needing electrical cardioversion and how long it takes. It will also show how many participants experience medical problems after treatment and how BAY 3670549 move into, through and out of the participants' body.
The total duration of the study for an individual participant may be up two months.
The findings from this study may contribute to the development of a new treatment option for people with AF.
| Facility | City | Region | Status |
|---|---|---|---|
| UCSF Advanced Heart Failure Comprehensive Care Center | San Francisco | California | Withdrawn |
| UCHealth University of Colorado Hospital - Cardiology | Aurora | Colorado | Not Yet Recruiting |
| Massachusetts General Hospital - Cardiology | Boston | Massachusetts | Not Yet Recruiting |
| Henry Ford Hospital - Cardiology | Detroit | Michigan | Not Yet Recruiting |
| Duke University Hospital - Cardiology | Durham | North Carolina | Not Yet Recruiting |
| Texas Health Heart and Vascular Specialists - Fort Worth | Fort Worth | Texas | Not Yet Recruiting |
| CHRISTUS Trinity | Mother Frances Louis and Peaches Owen Heart Hospital - Electrophysiology Clinic | Tyler | Texas | Withdrawn |
| UZ Leuven Gasthuisberg - Cardiology diseases department | Leuven | Flemish Brabant | Not Yet Recruiting |
| Jessa Ziekenhuis | Hartcentrum Hasselt | Hasselt | Limburg | Not Yet Recruiting |
| AZ Delta | Clinical Trial Center - Cardiology | Roeselare | West Flanders | Not Yet Recruiting |
| University Multiprofile Hospital For Active Treatment Sveti Georgi' - EAD Department of Intensive Cardiology" | Plovdiv | Plovdiv Province | Not Yet Recruiting |
| Multiprofile Hospital for Active Treatment Knyaginya Klementina Sofia EAD | Cardiology Department | Sofia | Sofia City Province | Not Yet Recruiting |
| University Hospital for Active Treatment Tsaritsa Joanna - ISUL | Cardiology Clinic | Sofia | Sofia City Province | Not Yet Recruiting |
| Multiprofile Hospital for Active Treatment Dr. Stefan Cherkezov | Base 1 - Cardiology Department | Veliko Tarnovo | Veliko Tarnovo Province | Not Yet Recruiting |
| Medizinische Hochschule Hannover|Kardiologie und Angiologie | Hanover | Lower Saxony | Not Yet Recruiting |
| Herz-und Diabeteszentrum NRW|Elektrophysiologie/Rhythmologie | Bad Oeynhausen | North Rhine-Westphalia | Not Yet Recruiting |
| Klinikum Altenburger Land GmbH-Klinik für Kardiologie, Pneumologie und Internistische Intensivmedizin | Altenburg | Thuringia | Not Yet Recruiting |
| Tolna Vármegyei Balassa János Kórház - I. Belgyógyászati Osztály: Kardiológia, Nefrológia | Szekszárd | Tolna County | Not Yet Recruiting |
| Semmelweis Egyetem, Varosmajori Sziv- és Ergyogyaszati Klinika | Budapest | Hungary | Not Yet Recruiting |
| Ente Ecclesiastico Ospedale Generale Regionale Miulli - Cardiologia e UTIC | Acquaviva delle Fonti | Italy | Not Yet Recruiting |
| Centro Cardiologico Monzino S.p.A. - UO Scompenso e Cardiologia Clinica | Milan | Italy | Recruiting |
| Azienda Ospedaliero-Universitaria Policlinico Umberto I - Malattie Cardiovascolari | Roma | Italy | Not Yet Recruiting |
| Azienda Ospedaliero Universitaria Delle Marche - Clinica di Cardiologia e Aritmologia | Torrette | Italy | Not Yet Recruiting |
| Maastricht UMC | Maastricht | Limburg | Not Yet Recruiting |
| Universitair Medisch Centrum Groningen | Groningen | Netherlands | Not Yet Recruiting |
| American Heart of Poland S.A. - PAKS Centrum Kardiologii i Kardiochirurgii w Bielsku-Białej - Oddział Kardiologii | Bielsko-Biala | Poland | Not Yet Recruiting |
| American Heart of Poland S.A. - MCSN, PAKS w Chrzanowie - Oddział Intensywnej Opieki Kardiologicznej | Chrzanów | Poland | Not Yet Recruiting |
| Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. sw. Jana Pawla II | Grodzisk Mazowiecki | Poland | Not Yet Recruiting |
| USK nr 4 w Lublinie - Kliniczny Odd. Kardiologii, Reh. Kardio., Ch. Wew. z Pododdzialem Intensywnej Opieki Kardio. | Lublin | Poland | Not Yet Recruiting |
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07625215 on ClinicalTrials.gov ↗ ← All trials in Poland