Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment

Condition(s) studied

Investigational drug(s) / intervention(s)

Exercise: All participants will be involved in the exercise training three times per week for 24 weeks: endurance exercise training, resistant exercise training

control: outcome measures

Study summary

This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control group

Eligibility

Primary outcome measure(s)

• Gait speed (6MWT) — through study completion, an average of 1 year
  • Assess the effect of exercise on physical performance and quality of life on pa-tients with chronic kidney disease from stage 1 to end stage renal disease on maintenance haemodialysis or on conservative treatment
• Physical performance (SPPB) — through study completion, an average of 1 year
• Cardiopulmonary capacity (CPET) — through study completion, an average of 1 year
• Lower limbs strength (1-RM) — through study completion, an average of 1 year
• Maximum isometric strength of the upper limb (hand grip) — through study completion, an average of 1 year
• Daily physical activity amount (IPAQ) — through study completion, an average of 1 year
• Quality of life (SF36) — through study completion, an average of 1 year

Trial sites (1)

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