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Trackers› Clinical trials› Advanced Solid Tumor
Clinical trial register · Italy

Advanced Solid Tumor Trials in Italy, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Italy and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 6830 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:52 UTC
6830
Studies in scope
all four open statuses
4109
Recruiting now
open to new participants
1019
Lead sponsors
across recruiting studies
Top sites
Milan 12 Naples 8 Rozzano 4 Meldola 3 Roma 3
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Recruitment status
Phase
Site location
Milan12 Naples8 Rozzano4 Meldola3 Roma3
All 24 locations
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Advanced Solid Tumor trials in Italy

17 of 6830 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Italy
Start
Recruiting
An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors
NCT07222267Breast Cancer, Advanced Solid Tumor
BeOne Medicines
Phase 1
86
Milan, Naples, Roma, Rozzano
2025-12-11
Recruiting
A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours
NCT06833008Advanced Solid Tumor
Ipsen
Phase 1/2
85
Milan, Naples
2025-03-14
Recruiting
Single Microdose Trial- CXCR4 PET Tracer - Pharmacokinetics and Pharmacodynamics of [68Ga]Ga-R54, a Radiopharmaceutical Directed Toward CXCR4 in Patients With Advanced Solid Neoplasia.
NCT07577206Advanced Solid Tumor, Multiple Myeloma
National Cancer Institute, Naples
Phase EARLY_PHASE1
10
Naples
2025-01-24
Active, closed
A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors (REJOICE-PanTumor01)
NCT06660654Advanced Solid Tumor, Metastatic Solid Tumors
DrugR-DXd
Daiichi Sankyo
Phase 2
335
Catania, Genova, Meldola, Milan, Naples, Terni
2025-01-06
Active, closed
A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors
NCT06607185Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer, Colorectal Cancer, Advanced Solid Tumor
Eli Lilly and Company
Phase 1
750
Verona
2024-10-21
Recruiting
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
NCT06172478Advanced Solid Tumor, Melanoma, Head and Neck Cancer, Gastric Cancer
Daiichi Sankyo
Phase 2
740
Bergamo, Genova, Naples, Verona
2024-02-26
Recruiting
SNV1521 in Participants With Advanced Solid Tumors
NCT06220864Advanced Solid Tumor
Synnovation Therapeutics, Inc.
Phase 1
400
Milan
2024-02-23
Recruiting
A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)
NCT06028724Solid Tumor, Advanced Solid Tumor, Locally Advanced Solid Tumor, Colon Rectal Cancer
Centro di Riferimento Oncologico - Aviano
Observational
782
Aviano
2023-05-26
Active, closed
Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors
NCT05462717Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Pancreatic Ductal Adenocarcinoma, Advanced Solid Tumor
Revolution Medicines, Inc.
Phase 1
222
Milan, Naples, Orbassano, Pavia, Verona
2022-09-19
Active, closed
First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours
NCT05495295Malignant Tumor, Advanced Solid Tumor, Glioblastoma Multiforme, Metastatic Cancer
Phost'In Therapeutics
Phase 1
149
Milan, Reggio Emilia
2022-07-18
Active, closed
A Study to Investigate Safety and Tolerability of TransCon IL-2 ฮฒ/ฮณ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
NCT05081609Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor, Platinum-resistant Ovarian Cancer
Ascendis Pharma Oncology Division A/S
Phase 1/2
320
Cuneo, Florence, Grosseto, Lido di Camaiore, Livorno, Meldola, Milan, Modena
2022-01-11
Recruiting
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT04585750Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor
PMV Pharmaceuticals, Inc
Phase 1/2
300
Rome, Milan, Rozzano, Candiolo, Naples
2020-10-29
Recruiting
Safety and Early Signs of Efficacy of IL12-L19L19.
NCT04471987Advanced Solid Tumor, Metastatic Solid Tumor
Philogen S.p.A.
Phase 1
80
Milan, Orbassano
2020-07-01
Recruiting
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
NCT04104776Advanced Solid Tumor, Diffuse Large B Cell Lymphoma, Lymphoma, T-Cell, Mesothelioma, Malignant
Novartis Pharmaceuticals
Phase 1/2
300
Bologna, Milan, Roma, Rozzano
2019-09-18
Recruiting
A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)
NCT03767075Advanced Solid Tumor
Vall d'Hebron Institute of Oncology
Phase 2
1,000
Milan
2018-12-10
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with an Italian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 28 September 2026. https://priyalifescience.com/clinical-trials-italy/condition/advanced-solid-tumor

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Italy and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,830 studies in total at the last sync on 26 Sep 2026, 19:52 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 17 of those studies listing the condition Advanced Solid Tumor.

How many Advanced Solid Tumor trials are recruiting in Italy?

11 of the 17 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:52 UTC sync. A further 0 have not yet opened recruitment, 6 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Advanced Solid Tumor), 17 studies
PhaseStudiesRecruitingShare
Phase 17341.2%
Phase 1/25429.4%
Phase 23217.6%
Observational115.9%
Phase EARLY_PHASE1115.9%

Most active sponsors

Lead sponsors with the most studies (Advanced Solid Tumor)
Lead sponsorStudiesRecruiting
Daiichi Sankyo31
Ascendis Pharma Oncology Division A/S10
BeOne Medicines11
BioNTech SE11
Centro di Riferimento Oncologico - Aviano11
Eli Lilly and Company10
Ipsen11
National Cancer Institute, Naples11
Novartis Pharmaceuticals11
Philogen S.p.A.11
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.