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Clinical trial register · Ireland

Studies with an Irish investigative site

Every study on the ClinicalTrials.gov registry that lists a site in Ireland and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 615 matching records held by the registry are in this view. Synced 22 Sep 2026, 03:15 UTC
615
Studies in scope
all four open statuses
323
Recruiting now
open to new participants
181
Lead sponsors
across recruiting studies
37
Irish site locations
across all listed studies
Phase mix of the 323 recruiting studies
Phase 3 98 Not applicable 79 Observational 76 Phase 2 30 Phase 1/2 20 Other 20
Narrow the register
Matches title, registry number, sponsor, intervention and condition.
Recruitment status
Phase
Lead sponsor
Merck Sharp & Dohme LLC 36 Royal College of Surgeons, Ireland 29 University College Dublin 21 AbbVie 20 University College Cork 19
Site location
Dublin 483 Cork 170 Galway 124 Limerick 56 Waterford 51
All 37 locations
Target enrolment
to
615 of 615 studies
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Status
Study
Lead sponsor
Phase
Enrol
Irish sites
Start
Recruiting
Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study.
NCT05074732 Schizophrenia, Forensic Psychiatry, Outcome Measure, Violence
Health Service Executive, Ireland
Observational
350
Dublin
2019-12-01
Active, closed
HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
NCT04153149 Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals
Phase 3
655
Dublin
2019-11-26
Active, closed
First in Human Clinical Investigation of the FIRE1 System in Heart Failure Patients (FUTURE-HF)
NCT04203576 Heart Failure
Foundry Innovation & Research 1, Limited (FIRE1)
Not applicable
50
Galway
2019-11-22
Active, closed
Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome
NCT04009330 Acute Respiratory Distress Syndrome (ARDS)
Queen's University, Belfast
Observational
480
Dublin
2019-11-22
Active, closed
Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock
NCT04055909 Shock, Septic
Inotrem
Phase 2
355
Dublin, Galway
2019-11-13
Active, closed
A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer
NCT04025879 Carcinoma, Non-Small-Cell Lung
Bristol-Myers Squibb
Phase 3
461
Dublin
2019-11-05
Active, closed
Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer
NCT03862911 Metastatic Tumors
British Columbia Cancer Agency
Not applicable
330
Rathgar, Dublin, Cork
2019-11-01
Recruiting
Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia
NCT04793919 Acute Promyelocytic Leukemia
Associazione Italiana Ematologia Oncologia Pediatrica
Phase 2
89
Dublin
2019-10-09
Active, closed
A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04033445 Ulcerative Colitis
Janssen Research & Development, LLC
Phase 2/3
1,064
Dublin, Galway
2019-09-26
Active, closed
Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT04095364 Low Grade Fallopian Tube Serous Adenocarcinoma, Ovarian Low Grade Serous Adenocarcinoma, Primary Peritoneal Low Grade Serous Adenocarcinoma, Stage II Fallopian Tube Cancer AJCC v8
NRG Oncology
Phase 3
450
Cork, Dublin
2019-09-20
Active, closed
An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial
NCT03844048 Chronic Lymphocytic Leukemia, Acute Myeloid Leukemia, Multiple Myeloma, Non-Hodgkin's Lymphoma
AbbVie
Phase 3
165
Dublin
2019-09-06
Recruiting
Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial
NCT03997643 Head and Neck Cancer
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Phase 2
90
Wilton, Galway, Rathgar, Dublin
2019-09-06
Recruiting
International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma
NCT04043494 Lymphoblastic Lymphoma, Childhood
University Hospital Muenster
Phase 3
683
Dublin
2019-08-23
Active, closed
A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation
NCT04002297 Mantle Cell Lymphoma; Non-Hodgkin Lymphoma
BeOne Medicines
Phase 3
510
Cork, Dublin, Galway, Limerick, Waterford
2019-08-20
Recruiting
Pan Tumor Rollover Study
NCT03899155 Cancer
Bristol-Myers Squibb
Phase 2
1,500
Dublin, Limerick
2019-08-09
Active, closed
A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)
NCT04008030 Metastatic Colorectal Cancer
Bristol-Myers Squibb
Phase 3
839
Dublin, Limerick
2019-08-05
Active, closed
Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)
NCT03924895 Urinary Bladder Cancer, Muscle-invasive
Merck Sharp & Dohme LLC
Phase 3
595
Dublin, Waterford
2019-07-24
Active, closed
A Multicenter, International, Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® PmVSD Occluder in Patients With Perimembranous Ventricular Septal Defects
NCT04034498 Perimembranous Ventricular Septal Defect
Occlutech International AB
Observational
50
Dublin
2019-07-07
Active, closed
A Research Study in Children Born Small and Who Stayed Small. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day
NCT03878446 Short Stature Children Born Small for Gestational Age (SGA)
Novo Nordisk A/S
Phase 2
62
Dublin
2019-07-04
Active, closed
SIRONA 2 Trial Heart Failure NYHA Class III
NCT04012944 Heart Failure NYHA Class III
Endotronix, Inc.
Not applicable
81
Dublin
2019-06-26
Recruiting
E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe
NCT03818503 Cancer
European Organisation for Research and Treatment of Cancer - EORTC
Observational
2,000
Dublin, Galway
2019-06-24
Active, closed
Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients With High Risk Cutaneous Squamous Cell Carcinoma
NCT03969004 Cutaneous Squamous Cell Carcinoma
Regeneron Pharmaceuticals
Phase 3
415
Dublin, Cork, Galway
2019-06-04
Active, closed
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
NCT03253263 Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Intraventricular Hemorrhage, Retinopathy of Prematurity (ROP)
OHB Neonatology Ltd.
Phase 2
295
Cork
2019-05-09
By invitation
Zoledronate In the Prevention of Paget's Disease: Long Term Extension
NCT03859895 Paget Disease
University of Edinburgh
Observational
287
Dublin
2019-04-05
Active, closed
Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children in the United Kingdom
NCT03690089 Myopia
Belfast Health and Social Care Trust
Phase 2
289
2019-04-03
Active, closed
Phase III Study in First-line Treatment of Patients With Metastatic Colorectal Cancer Who Are Not Candidate for Intensive Therapy.
NCT03869892 Metastatic Colorectal Cancer
Institut de Recherches Internationales Servier
Phase 3
856
Cork, Dublin
2019-03-21
Active, closed
A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer
NCT03816163 Pancreatic Cancer, Metastatic Pancreatic Cancer, Metastatic Pancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc.
Phase 2
393
Elm Park
2019-03-15
Active, closed
A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy
NCT03839771 Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts-2
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
968
Cork, Dublin, Galway
2019-03-01
Recruiting
The Mechanical Characterisation of Human Saphenous and Popliteal Vein
NCT04016649 Peripheral Vascular Diseases
University Hospital of Limerick
Observational
50
Limerick
2019-01-21
Active, closed
Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX
NCT03754790 Hemophilia
Genzyme, a Sanofi Company
Phase 3
281
Crumlin, Dublin
2019-01-09
Active, closed
Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)
NCT03725059 Breast Cancer
Merck Sharp & Dohme LLC
Phase 3
1,240
Cork, Dublin
2018-12-27
Active, closed
Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)
NCT03765918 Head and Neck Neoplasms
Merck Sharp & Dohme LLC
Phase 3
714
Dublin
2018-12-17
Active, closed
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension
NCT03614260 Hypertension, Vascular Diseases, Cardiovascular Diseases
ReCor Medical, Inc.
Not applicable
225
Galway
2018-12-14
Active, closed
Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)
NCT03742895 Advanced Solid Neoplasms
Merck Sharp & Dohme LLC
Phase 2
329
Dublin, Cork
2018-12-12
Active, closed
A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer
NCT03701334 Early Breast Cancer
Novartis Pharmaceuticals
Phase 3
5,101
Wilton, County Limerick, Dublin, Waterford
2018-12-07
Active, closed
A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).
NCT03653507 Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
Astellas Pharma Global Development, Inc.
Phase 3
507
Dublin
2018-11-28
Active, closed
Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer
NCT03539536 Non-small Cell Lung Cancer
AbbVie
Phase 2
270
Wilton, Dublin, Elm Park
2018-10-10
Recruiting
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
NCT04174157 Spinal Muscular Atrophy (SMA)
Novartis Pharmaceuticals
Observational
700
Dublin
2018-09-25
Active, closed
Feasibility Study of the Pilot Post-primary Active School Flag (PPASF) Program
NCT03847831 Physical Activity, Health Behavior, Health Knowledge, Attitudes, Practice, Educational Problems
University of Limerick
Not applicable
9,000
Limerick
2018-09-01
Recruiting
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
NCT03486873 Solid Tumors, Hematologic Malignancies
Merck Sharp & Dohme LLC
Phase 3
3,500
Dublin
2018-08-21
Recruiting
A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)
NCT02991469 Juvenile Idiopathic Arthritis
Sanofi
Phase 2
51
Crumlin
2018-08-09
Active, closed
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
NCT03568318 Atopic Dermatitis
AbbVie
Phase 3
1,533
Dublin, Cork, Waterford
2018-08-09
Active, closed
A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)
NCT03519945 Ulcerative Colitis
Eli Lilly and Company
Phase 3
1,058
Dublin
2018-07-18
Active, closed
Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy
NCT03755791 Hepatocellular Carcinoma
Exelixis
Phase 3
837
Dublin
2018-06-10
By invitation
Feasibility of Switching Fluoropyrimidine Due to Cardiotoxicity Study
NCT04260269 Solid Tumor
Helsinki University Central Hospital
Observational
200
Dublin
2018-06-01
Active, closed
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
NCT03523858 Progressive Multiple Sclerosis (PMS)
Hoffmann-La Roche
Phase 3
927
Cork, Dublin
2018-05-28
Active, closed
A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
NCT03522246 Epithelial Ovarian Cancer, Primary Peritoneal, Fallopian Tube Cancer, Newly Diagnosed
pharmaand GmbH
Phase 3
1,097
Cork, Limerick, Waterford
2018-05-14
Active, closed
Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)
NCT03425643 Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC
Phase 3
797
Wilton, Dublin, Limerick
2018-04-24
Active, closed
Pyruvate Kinase Deficiency Global Longitudinal Registry
NCT03481738 Pyruvate Kinase Deficiency
Agios Pharmaceuticals, Inc.
Observational
500
Dublin
2018-04-23
Active, closed
A Study of the Efficacy and Safety of Risankizumab in Participants With Crohn's Disease
NCT03105102 Crohn's Disease
AbbVie
Phase 3
1,336
Beaumont, Elm Park, Galway
2018-04-09
Active, closed
A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433
NCT03345823 Crohn's Disease
AbbVie
Phase 3
747
Cork
2018-03-21
Active, closed
To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.
NCT03330847 Metastatic Triple Negative Breast Cancer
AstraZeneca
Phase 2
273
Cork, Dublin
2018-03-07
Active, closed
Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer
NCT03367702 Stage II Prostate Adenocarcinoma AJCC v7
NRG Oncology
Phase 3
692
Dublin
2018-02-01
Active, closed
ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population
NCT03153449 Primary Knee Arthroplasty
DePuy Orthopaedics
Not applicable
400
Cork
2017-09-19
Recruiting
Registry for Patients With X-Linked Hypophosphatemia
NCT03193476 X-Linked Hypophosphatemia
Kyowa Kirin Pharmaceutical Development Ltd
Observational
1,489
Dublin
2017-09-12
Active, closed
Paediatric Hepatic International Tumour Trial
NCT03017326 Hepatoblastoma, Carcinoma, Hepatocellular
University of Birmingham
Phase 3
450
Dublin
2017-08-24
Active, closed
EXamining PErsonalised Radiation Therapy for Low-risk Early Breast Cancer
NCT02889874 Early Stage Breast Carcinoma
Breast Cancer Trials, Australia and New Zealand
Not applicable
1,167
Dublin, Galway
2017-08-21
Recruiting
International Registry for Men With Advanced Prostate Cancer (IRONMAN)
NCT03151629 Prostate Cancer
Prostate Cancer Clinical Trials Consortium
Observational
5,000
Dublin, Sligo
2017-07-21
Active, closed
The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)
NCT03171311 Ischaemic Heart Disease, Ischemic Heart Disease
Aarhus University Hospital Skejby
Not applicable
1,201
Galway
2017-07-05
Active, closed
ATTUNE Revision System in the Revision Total Knee Arthroplasty Population
NCT03153475 Revision Total Knee Arthroplasty
DePuy Orthopaedics
Not applicable
400
Cork
2017-05-30
Recruiting
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
NCT03072927 Lumbar Spinal Stenosis
Stryker Instruments
Observational
8,000
2017-03-10
Active, closed
Optimal Nutrition for Prevention of Hypertension in Pregnancy
NCT04723836 Blood Pressure, Pregnancy
University of Ulster
Not applicable
2,250
Letterkenny
2017-03-01
Active, closed
A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
NCT03006068 Ulcerative Colitis (UC)
AbbVie
Phase 3
950
Dublin, Elm Park, Cork, Galway
2017-01-31
Active, closed
Lenvatinib/Everolimus or Lenvatinib/Pembrolizumab Versus Sunitinib Alone as Treatment of Advanced Renal Cell Carcinoma
NCT02811861 Renal Cell Carcinoma
Eisai Inc.
Phase 3
1,069
Cork, Dublin, Galway
2016-10-13
Active, closed
14022 ATTUNE Cementless RP Clinical Performance Evaluation
NCT02839850 Osteoarthritis
DePuy Orthopaedics
Not applicable
540
Cork
2016-09-01
Active, closed
A Study of Niraparib (GSK3985771) Maintenance Treatment in Participants With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy
NCT02655016 Ovarian Neoplasms
Tesaro, Inc.
Phase 3
733
Dublin, Dunmore RoadWaterford, Galway
2016-07-11
Active, closed
PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer
NCT03469674 Endometrial Cancer Stage I, Endometrial Cancer Stage II
Leiden University Medical Center
Phase 3
550
Dublin
2016-06-10
Recruiting
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
NCT02735707 Community-acquired Pneumonia, Influenza, COVID-19
UMC Utrecht
Phase 3
20,000
Cork, Dublin, Galway, Waterford
2016-04-11
Active, closed
International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia
NCT02724163 Acute Myeloid Leukaemia
University of Birmingham
Phase 3
700
Dublin
2016-04
Recruiting
The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue
NCT05802706 Vascular Diseases
University Hospital of Limerick
Observational
300
Limerick
2016-01-01
Active, closed
Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers
NCT02785952 Recurrent Squamous Cell Lung Carcinoma, Stage IV Squamous Cell Lung Carcinoma AJCC v7
SWOG Cancer Research Network
Phase 3
275
2015-12-29
Active, closed
A Study to Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumors With NTRK-fusion in Children
NCT02637687 Solid Tumors Harboring NTRK Fusion
Bayer
Phase 1/2
154
Crumlin
2015-12-16
Active, closed
A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Adults With Rheumatoid Arthritis Who Are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate
NCT02629159 Rheumatoid Arthritis
AbbVie
Phase 3
1,629
Dublin
2015-12-01
Active, closed
Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery
NCT02506153 Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Cutaneous Melanoma, Metastatic Mucosal Melanoma
National Cancer Institute (NCI)
Phase 3
1,301
Dublin, Galway, Waterford
2015-11-10
Recruiting
Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis
NCT05663008 ALS (Amyotrophic Lateral Sclerosis), Postpoliomyelitis Syndrome, Spinal Muscular Atrophy
University of Dublin, Trinity College
Observational
400
Dublin
2015-10-01
Active, closed
Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours
NCT02804815 Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer
University College, London
Phase 3
11,000
Cork, Dublin, Galway, Limerick, Sligo, Waterford
2015-10
Active, closed
Phase III Radium 223 mCRPC-PEACE III
NCT02194842 Prostate Cancer
European Organisation for Research and Treatment of Cancer - EORTC
Phase 3
446
Cork, Dublin
2015-10
Active, closed
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors
NCT02375204 Germ Cell Tumor, Teratoma, Choriocarcinoma, Germinoma
Alliance for Clinical Trials in Oncology
Phase 3
420
Dublin
2015-08-06
Active, closed
PALbociclib CoLlaborative Adjuvant Study
NCT02513394 Breast Cancer
Alliance Foundation Trials, LLC.
Phase 3
5,796
Cork, Dublin, Limerick, Sligo, Waterford
2015-08
Active, closed
CompARE: Escalating Treatment of Intermediate and High-risk Oropharyngeal Cancer (OPC)
NCT04116047 Oropharyngeal Cancer
University of Birmingham
Phase 3
785
Dublin
2015-07
Recruiting
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma
NCT02265770 Childhood Ependymoma
Centre Leon Berard
Phase 2/3
536
Dublin
2015-06-02
Active, closed
Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients
NCT02362503 HIV Infections
ViiV Healthcare
Phase 3
371
Dublin
2015-02-23
Active, closed
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer
NCT02308085 Early Breast Cancer
ETOP IBCSG Partners Foundation
Not applicable
518
Dublin, Galway, Limerick, Waterford
2014-12-04
Active, closed
A Non-Interventional Clinical Study to Evaluate Long-Term Safety and Effectiveness of HUMIRA (Adalimumab) in Pediatric Patients With Moderately to Severely Active Crohn's Disease (CD)
NCT02130362 Crohn's Disease
AbbVie
Observational
1,446
Manorhamilton
2014-08-28
Active, closed
International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
NCT02066220 Brain Tumors
Universitätsklinikum Hamburg-Eppendorf
Phase 2/3
360
Dublin
2014-06
Recruiting
The European Paediatric Network for Haemophilia Management ( PedNet Registry)
NCT02979119 Factor VIII Deficiency, Factor IX Deficiency
PedNet Haemophilia Research Foundation
Observational
4,000
Dublin
2014-06
Active, closed
Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer
NCT02446405 Prostatic Neoplasms
University of Sydney
Phase 3
1,125
Beaumont, Dublin, Galway, Tallaght, Waterford
2014-03
Active, closed
Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer
NCT02446444 Prostatic Neoplasms
University of Sydney
Phase 3
802
Cork, Galway, Dublin
2014-03
Recruiting
Biomechanical Analysis of Dynamic Tasks and Muscular Strength Following Anterior Cruciate Ligament Reconstruction
NCT02771548 Rupture of Anterior Cruciate Ligament
Dr Neil Welch ASCC
Observational
1,000
Dublin
2014-01
Active, closed
TAILORx Tissue Bank
NCT02050750 Breast Cancer
Cancer Trials Ireland
Observational
600
Cork, Donegal, Dublin, Galway, Limerick, Sligo, Waterford
2013-12
Active, closed
A Phase III Study for Patients With Metastatic Hormone-naïve Prostate Cancer
NCT01957436 Metastatic Prostate Cancer
UNICANCER
Phase 3
1,173
Cork, Dublin, Galway
2013-11-13
Recruiting
A Long-term Extension Study of PCI-32765 (Ibrutinib)
NCT01804686 Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, Follicular Lymphoma
Janssen Research & Development, LLC
Phase 3
700
Dublin
2013-09-09
Active, closed
Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery
NCT01872975 Stage IB Breast Cancer, Stage II Breast Cancer
NSABP Foundation Inc
Not applicable
1,636
Dublin, Galway
2013-08
Recruiting
European Registry on the Management of Helicobacter Pylori Infection
NCT02328131 H. Pylori Infection
Javier P. Gisbert
Observational
10,000
Dublin
2013-06
Recruiting
Lysosomal Acid Lipase (LAL) Deficiency Registry
NCT01633489 Lysosomal Acid Lipase Deficiency, Cholesterol Ester Storage Disease, Wolman Disease, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2
Alexion Pharmaceuticals, Inc.
Observational
300
Dublin
2013-05-30
Active, closed
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
NCT01848561 Ulcerative Colitis (UC)
AbbVie
Observational
8,250
Abbotstown, Dublin, Elm Park, Galway
2013-04-29
Recruiting
Breast Cancer Proteomics and Molecular Heterogeneity
NCT01840293 Primary Breast Cancer, Recurrent/Metastatic Breast Cancer
Cancer Trials Ireland
Observational
1,780
Cork, Dublin, Limerick, Waterford
2013-02
Active, closed
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001
NCT01760005 Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Washington University School of Medicine
Phase 2/3
490
Dublin
2012-12
Active, closed
Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma
NCT01415752 Lymphoma, Mantle Cell Lymphoma
Eastern Cooperative Oncology Group
Phase 2
373
2012-08-09
Active, closed
Prostate Advances in Comparative Evidence
NCT01584258 Prostate Cancer
Royal Marsden NHS Foundation Trust
Phase 3
2,205
Dublin
2012-08-07
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Priya Life Science (2026). Clinical trial register: studies with an Irish investigative site. Derived from ClinicalTrials.gov, U.S. National Library of Medicine. Retrieved 22 September 2026. https://priyalifescience.com/clinical-trials-ireland?page=6

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Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. For trials across the wider EU, see the EU Clinical Trials Tracker.