This study investigates the longitudinal effects of brain stimulation treatments on decision-making and reward learning. Here, we use daily assessments of reinforcement learning behavior in patients with depression who receive neuromodulation treatment to study potential associations between changes in decision-making and reward learning and changes in clinical symptoms.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Indication for a brain stimulation treatment (ECT, TMS, VNS, taVNS) in the Department of Psychiatry and Psychotherapy at the University Hospital Bonn
* Be able and willing to provide informed consent.
Exclusion Criteria:
* Non-German speakers
* Unclear ability to give consent to the study participation
Primary outcome measure(s)
Punishment learning rates — Assessed online up to 5 times before the first stimulation treatment and daily throughout the study (8 weeks). The primary outcome are punishment learning rate estimates from a computational reinforcement learning model. Learning rates will be compared within and between stimulation conditions. Reinforcement learning is repeatedly measured with a bandit task with fluctuating reward probabilities (reward learning task). Reward learning behavior will be collected online over up to 60 runs, each including 150 trials.
Trial sites (1)
Facility
City
Region
Status
Section of Medical Psychology, Department of Psychiatry & Psychotherapy, Faculty of Medicine, University of Bonn
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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