ControlBFR Exercise (50% of the LOP) while Leg Press Exercise (4 Sets, All out)
Control: Sham-BFR Exercise (20mmHg) while Leg Press Exercise (4 Sets, All out)
BFR Exercise (50% of the LOP) while Leg Press Exercise (4 Sets, All out): BFR Exercise (50% of the LOP) while Leg Press Exercise (4 Sets, All out)
Study summary
In the course of a cross-over study design, 12 patients with hemophilic arthropathy will perform a training load on the knee extensor muscles. The subjects will each perform one intervention with blood flow restriction and one with a Sham-BFR intervention.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* patients with haemophilia
* Ability for an exercise intervention
Exclusion Criteria:
* Sickle Cell Anemia
* Intravascular stents/bypasses
* Open Wounds/Infections of the lower extremity
Primary outcome measure(s)
Pain threshold — Pre- (Baseline, before Exercise) to immediately Post-Intervention (after the exercise training intervention) and 24 hours after intervention Pain threshold measurement (PTT): The test determines the amount of pressure (in kg) over a given area in which a steadily increasing nonpainful pressure stimulus turns into a painful pressure sensation.
Quality of Life Score — Pre- (Baseline, before Exercise) to immediately Post-Intervention (after the exercise training intervention) and 24 hours after intervention Hemophilia Joint Health Score
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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