The Impact of Endoscopic Endonasal Skull Base Surgery on Olfaction

Condition(s) studied

Investigational drug(s) / intervention(s)

Endoscopic endonasal skull base surgery: This intervention will be performed as part of the standard-of-care for patients scheduled for endoscopic endonasal skull base surgery for lesions in the (para)sellar region

Study summary

In this study, the research team will investigate the incidence and etiology of olfactory dysfunction following endoscopic endonasal skull base surgery, by combining clinical assessments with histomolecular analysis.

Eligibility

Primary outcome measure(s)

• Incidence of olfactory dysfunction — From enrollment to the last evaluation 6 months postoperatively
• Incidence of trigeminal dysfunction — From enrollment to the last evaluation 6 months postoperatively
• Etiology of olfactory and trigeminal dysfunction following endoscopic endonasal skull base surgery — Until the end of study (at 3 years)

Trial sites (3)

More Universitaire Ziekenhuizen KU Leuven trials in Germany

Other trials for the same condition