Ablation of Consecutive Atrial Tachycardia

NCT05239364 · tracked via the Priya Life Science Germany tracker

Sponsor

Evangelical Hospital Düsseldorf

Phase

Not applicable

Started

2020-12-22

Last updated

2026-04-30

Condition(s) studied

Heart ArrhythmiaHeart DiseasesArrhythmias, CardiacAtrial Tachycardia

Investigational drug(s) / intervention(s)

Catheter ablation

Catheter ablation: Catheter-based ablation of arrhythmias using radiofrequency.

Study summary

Ablation of consecutive atrial tachycardia (AT) after ablation of atrial fibrillation (AF) or cardiac surgery can be challenging due to complex substrate and AT mechanisms. A substantial portion of patients is known to show various tachycardias and recurrences occur in a noticeable number of cases. With the availability of novel ultra-high-density mapping techniques characterization and understanding of AT mechanisms and underlying substrate can be improved. Aim of this prospective, multi-center, randomized study is to compare a standard AT ablation approach versus minimalized ablation of the clinical AT in regards to arrhythmia free survival.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Consecutive AT subsequent to prior AF ablation procedure or cardiac surgery * Surface ECG-documentation of AT as primary clinical arrhythmia * ECG indicating stable, map-able AT (stable activation sequence, and CL stability) with cycle length ≥ 200ms Exclusion Criteria: * \< 18 years * No previous atrial fibrillation ablation procedure or cardiac surgery * Pregnant women or women of childbearing potential without a negative pregnancy test within 48 hours prior to treatment * History of hemorrhagic diathesis or other coagulopathies * Contraindications for oral anticoagulation * Hyper- or hypothyroidism * Has any condition that would make participation not be in the best interest of the subject

Primary outcome measure(s)

Recurrence of any sustained arrhythmia (>30 sec.) — 1 year

Trial sites (6)

Facility	City	Region	Status
Asklepios St. Georg	Hamburg	Free and Hanseatic City of Hamburg	Recruiting
Evangelic Hospital Düsseldorf	Düsseldorf	North Rhine-Westfalia	Recruiting
Vivantes Klinikum Am Urban Berlin	Berlin	Germany	Recruiting
Evangelic Hospital Hagen-Haspe	Hagen	Germany	Recruiting
Städtisches Klinikum Karlsruhe	Karlsruhe	Germany	Recruiting
Universitätsklinikum Schleswig Holstein	Kiel	Germany	Recruiting

More Evangelical Hospital Düsseldorf trials in Germany

Systematic Assessment of Treatment Effectiveness for Long-Term Management of Stable Atrial Tachycardia in Inpatient and Outpatient Environments Active, not recruiting

Optimizing Quality of Life by Improved Patient Expectation Following Atrial Fibrillation Catheter Ablation Recruiting

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Clinical and Healthcare Economic OutcoMes From ReAl-worlD Use in Europe of an AI Software During AF Ablation Active, not recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05239364 on ClinicalTrials.gov ↗ ← All trials in Germany