Detection of Microplastics in Human Granulosa Cells and in the Follicular Fluid of Women Undergoing ICSI Treatment

Condition(s) studied

Investigational drug(s) / intervention(s)

Microplastics: Detection of microplastics as a yes/no value

Study summary

Plastic products have been used ubiquitously in the modern world for many decades - for example as packaging materials, textile fibers or molded parts. The general use and especially the improper disposal lead to enormous environmental pollution almost everywhere on earth.

Microplastics mainly originate from fragmentation of larger plastic objects or can be produced directly for the use in e.g. cosmetics or industrial dyes.

Microplastics have already been detected in fresh- and seawater, soil, food, but also in human blood and urine. The accumulation of microplastics in ovarian and testicular tissue in humans has not yet been investigated.

Eligibility

Primary outcome measure(s)

• Detection of microplastics in human granulosa cells and in the Follicular fluid — 1 day (directly after oocyte pick-up)
  Detection of microplastics in human granulosa cells and in the Follicular fluid of women undergoing intracytoplasmic sperm injection (ICSI) treatment as a binary value (yes / no).

Trial sites (1)

More Infertility Treatment Center Dortmund trials in Germany