Neuropsychological assessment and structural MRI: Complex neuropsychological assessment testing attentional and memory functions. Additionally, a structural MRI is measured.
Study summary
Neuropsychological and functional long-term consequences of subarachnoid hemorrhages (SAH) represent a great challenge, since sometimes considerable cognitive deficits occur without evidence of substantial brain damage. In this study, we want to examine if the frequently observed memory deficits are associated with hippocampal atrophy.
Eligibility
Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria:
* neurological rehabilitation patients in phase B - D
* at minimum eight weeks after disease onset
* aneurysmal subarachnoid hemorrhage (Hunt \& Hess grade I or II)
* written consent from the patient's legal representative
* exclusion of pregnancy
Exclusion Criteria:
* insufficient cardiorespiratory stability
* previous brain damage
* mental disorders (dementia, depression)
* colonization with multi-resistant pathogens
* MRI contraindications
* claustrophobia
* weight \> 120 kg
Primary outcome measure(s)
Changed hippocampal volume in aSAB — 2 weeks Hypothesis: patients have smaller hippocampal volume than healthy control subjects. For the hippocampal volume a structural MRI scan (3D-MPRAGE) is obtained
Trial sites (1)
Facility
City
Region
Status
BDH-Clinic Hessisch Oldendorf
Hessisch Oldendorf
Germany
Recruiting
More BDH-Klinik Hessisch Oldendorf trials in Germany
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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