The objective of the European Confederation of Medical Mycology - ECMM Candida Registry (CandiReg) is to overcome the lack of knowledge on epidemiology, clinical course, and molecular characteristics of invasive infections due to invasive Candida infections and to function as a platform for future studies and in case of outbreaks.
Eligibility
Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Cultural, histopathological, antigen or DNA evidence of invasive fungal infection with Candida species.
* Hepatosplenic candidiasis with signs of disseminated Candida infection without culture, histological or microscopic evidence
* Case control
Matching procedure for controls:
In part, controls will be included at the same hospitals that include cases (i.e. each one control per case, both in the same hospital).
Controls will be matched by demographics, underlying diseases and risk factors as well as duration of hospitalization
Exclusion Criteria:
\- Colonization or other non-invasive infection, including superficial skin infections, candiduria without dissemination or Candida spp. in stool.
Primary outcome measure(s)
Incidence — up to 100 weeks To describe the global incidence of invasive Candida infection
Mortality — up to 100 weeks To describe the global mortality of invasive Candida infection
Molecular characteristics of Candida auris — At 90 Days from diagnosis To describe the molecular characteristics of Candida auris
Susceptibility testing — At 90 Days from diagnosis To describe the susceptibility of Candida auris
Resistance development — up to 100 weeks To describe the resistance development of Candida auris
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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