Colorectal Cancer PreventionColorectal Cancer (Diagnosis)Colorectal Adenocarcinoma
Investigational drug(s) / intervention(s)
ColonoscopyQuestionnairesPre-colonoscopy diet according to the investigator's oral instructionsPre-colonoscopy diet by following a special preparation, Colobox.
Colonoscopy: Colonoscopy performed and Boston score evaluated
Pre-colonoscopy diet according to the investigator's oral instructions: 24 hours before the colonoscopy, The patients follow a special diet, either by themselves according to the investigator's oral instructions
Pre-colonoscopy diet by following a special preparation, Colobox.: 24 hours before the colonoscopy, The patients follow a special diet, by following a special preparation, Colobox.
Study summary
Low-residue diet (LRD) in patient improves the quality of the colon cleanliness and thus the adenoma detection rate (ADR). This is a key criterion in colonoscopy screening for colorectal cancer (CRC). The benefit of an LRD lasting more than 24 hours before colonoscopy has not been demonstrated compared to a 24-hour LRD.
Few studies have evaluated the benefit of a prepackaged 24-hour LRD compared to simply receiving oral and written LRD instructions during a consultation.
The aim of the study is to evaluate the usefulness of a prepackaged LRD (Colobox®) compared to simple LRD instructions on colon cleanliness (Boston score) in patients examined by endoscopy.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Patient of one of the investigators for total colonoscopy (no prior colonic surgery);
* Patient aged 18 years or older;
* Patient classified as ASA 1, ASA 2, or ASA 3;
* Not participating in any other current clinical trial;
* Free, informed, and signed consent;
* Patient affiliated with or a beneficiary of a social security scheme, according to Article L.1124-1 of the French Public Health Code;
Exclusion Criteria:
* Patient taking major psychotropic medications;
* Patient with uncontrolled diabetes;
* Patient with coagulation abnormalities preventing polypectomy: PT \<50%, Platelets \<50,000/mm³, current effective anticoagulation therapy (clopidogrel, prasugrel, or ticagrelor);
* Patient referred for removal of a known polyp;
* Chronic inflammatory bowel disease;
* Known colonic stenosis;
* Diverticulitis of less than 6 weeks duration;
* Pregnant, parturient, or breastfeeding woman;
* Patient deprived of liberty by administrative or judicial order, or under guardianship or limited legal protection;
* Patient unable to understand the objectives and constraints of the study.
Primary outcome measure(s)
Boston Score — 1 day A 9-point system, helps them see how clean a patient's large intestine is during a colonoscopy. This scale divides the large intestine into three parts: right, middle, and left.
Each part can score from :
BBPS = 0 (per segment) : unprepared colon segment with mucosa not seen because of solid stool that cannot be cleared.
BPPS=3 (per segment) : entire mucosa of the colon segment seen well, with no residual staining, small fragments of stool, or opaque liquid.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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