Colorectal Cancer ScreeningColorectal Cancer PreventionColorectal Cancer
Investigational drug(s) / intervention(s)
Diet and lifestyle advice following a positive FIT test and diagnostic colonoscopy
Diet and lifestyle advice following a positive FIT test and diagnostic colonoscopy: Participants will be recruited during CRC screening and will be included if they have a positive faecal immunochemical test (FIT) and are diagnosed with adenomas but are CRC negative during the colonoscopy. Participants receive evidence-based diet and lifestyle advice intervention with 'usual care'
Study summary
The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may be at higher risk for colorectal cancer (CRC). The specific objectives of this study are to 1) develop a lifestyle intervention based on evidenced-based diet and lifestyle recommendations (i.e. those proposed by the World Cancer Research Fund (WCRF) and the French National Cancer Institute); 2) evaluate the effect of the intervention on the adherence to the target diet and lifestyle recommendations as well as other subjective health measures, including quality of life; 3) evaluate the effect of the intervention on anthropometrics.
Eligibility
Sex
ALL
Min age
35 Years
Max age
74 Years
Healthy volunteers
No
Inclusion Criteria:
* Having read the information note and agreeing to participate
* Will and availability to be committed for a full year
* At high risk for CRC but CRC negative
* Affiliated to a health security system
* Having a score on the adherence to the recommendation lower than or equal to 7 out of 9 at baseline.
* Able to read, write and understand French
Exclusion Criteria:
* Under a strict diet such as meal replacements, diets for co-morbidities such as diabetes
* Immobile due to physical constraints (e.g. handicap that is not compatible with physical activities)
* Extensive intestinal surgery such as colectomy or surgical resection of the colon
* Chronic gastrointestinal illness (IBD, IBS, celiac disease)
* Colorectal cancer confirmed or history of a primary cancer
* Severe malnutrition
* Pregnant
* Participation in another lifestyle study
NB : For this study, there is no exclusion period from other research, and participants can simultaneously take part in another study unless it concerns lifestyle.
Primary outcome measure(s)
Adherence to the evidence-based lifestyle recommendations — 3 months The primary outcome of the trial will be adherence to the evidence-based lifestyle recommendations (expressed as an adherence score on the individual lifestyle recommendations).
Score :
* unabbreviated scale title : World Cancer Research Fund's (WCRF)
* minimum value = 0 (more unhealthy behaviours) / maximum value = 7 (more healthy behaviours)
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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