Nd:YAG Laser Combined With Injection Sclerotherapy Versus Diode Laser in the Treatment of Reticular Veins and Telangiectasias Using CLaCS Technique

NCT07678697 · tracked via the Priya Life Science Egypt tracker

Sponsor

Ain Shams University

Phase

Not applicable

Started

2026-06-01

Last updated

2026-07-01

Condition(s) studied

Nd:YAG LaserSclerotherapyDiode LaserReticular VeinsTelangiectasiasCLaCS Technique

Investigational drug(s) / intervention(s)

Nd:YAG laserDiode laser

Nd:YAG laser: Patients will receive Nd:YAG laser (1064 nm) + injection sclerotherapy (CLaCS).

Diode laser: Patients will receive Diode laser (980 nm) + injection sclerotherapy (CLaCS).

Study summary

This study aims to compare the efficacy (in terms of vein clearance) and safety of Nd:YAG laser combined with injection sclerotherapy versus diode laser combined with injection sclerotherapy in the treatment of reticular veins and telangiectasias using the Cryo-Laser and Cryo-Sclerotherapy (CLaCS) technique.

Eligibility

Sex

ALL

Min age

18 Years

Max age

60 Years

Healthy volunteers

Inclusion Criteria: * Patients aged 18-60 years. * Both sexes. * Presence of reticular veins and/or telangiectasias (CEAP classification C1). * Fitzpatrick skin types II-V. * Patients seeking cosmetic treatment. Exclusion Criteria: * Pregnancy or lactation. * History of deep vein thrombosis. * Coagulation disorders. * Allergy to sclerosant agents. * Active skin infection at treatment site. * Previous treatment of target veins within 6 months. * Great saphenous vein or short saphenous vein incompetence. * Deep venous insufficiency or thrombosis. * Abnormal venous duplex findings.

Primary outcome measure(s)

Degree of vein clearance — 6 months postoperatively
Degree of vein clearance will be assessed by immediate endpoint response during laser application, defined as either instantaneous disappearance of the vein or an immediate change in vein color.

Trial sites (1)

Facility	City	Region	Status
Ain Shams University	Cairo	Egypt	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07678697 on ClinicalTrials.gov ↗ ← All trials in Egypt