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Clinical Trials in Egypt / NCT07535047
Recruiting Not applicable

Placebo-Induced Hypoalgesia During Transcutaneous Electrical Nerve Stimulation Application in Low Back Pain

NCT07535047 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2026-04-05
Last updated
2026-04-16

Condition(s) studied

Low Back Pain (LBP)Low Back Pain

Investigational drug(s) / intervention(s)

TENSTENS educational explanation videoExercise

TENS: 12 sessions of TENS each lasting 45 minutes ,will be conducted over a 4-week intervention period .

TENS educational explanation video: The video provides standardized information on TENS, demonstrating its use, safety, and how it modulates pain through gate control theory

Exercise: Participants will be provided with a home program consisting of exercises targeting trunk core activation, spinal mobility, and functional movement, as approved by the American Physical Therapy Association (APTA).

Study summary

The primary goal of this clinical trial is to evaluate the feasibility of conducting a full-scale randomized controlled trial (RCT), considering recruitment, compliance with study protocols, and adverse events. The secondary goal is to evaluate the effectiveness of a video-based educational explanation of transcutaneous electrical nerve stimulation (TENS) in eliciting placebo-induced hypoalgesia and improving clinical outcomes in patients with acute low back pain.

The main question it aims to answer is: Does the addition of a video-based educational explanation of TENS to standard physical therapy rehabilitation, consisting of TENS and exercises, increase the pressure pain threshold, reduce pain intensity, and improve functional mobility, patient satisfaction, and quality of life in patients with acute low back pain?

Participants will be divided into two groups for comparison: the control group will receive standard physical therapy rehabilitation consisting of TENS and exercises, while the experimental group will receive the same program in addition to the video-based educational explanation of TENS.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * acute low back pain without radicular pain to lower limbs * minimal pain level of 4 on the 0-10 VAS * 18-65 years of age * TENS naïve or have not used TENS in the past 5 years. Exclusion Criteria: * Radicular pain to lower limbs * Serious spinal disorders, such as fractures, tumors, or inflammatory arthritis disease * Nerve root disorders confirmed by neurological tests * Neurological diseases * Severe cardiorespiratory disease * Pregnancy * Skin infection or lesions or change in sensation at the TENS application site * Cancer * Cardiac pacemaker * Allergy to electrodes * use of opioids.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Cairo University Hospitals Giza Giza Governorate Recruiting

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Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07535047 on ClinicalTrials.gov ↗ ← All trials in Egypt