Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer Outcomes

NCT07499817 · tracked via the Priya Life Science Egypt tracker

Sponsor

Beni-Suef University

Phase

Phase 3

Started

2023-10-01

Last updated

2026-03-30

Condition(s) studied

Embryo TransferIVFInfertility

Investigational drug(s) / intervention(s)

pentoxifylline 400 mg →(control)

pentoxifylline 400 mg: Once daily in form of (Trental ® Sanofi co.) daily in addition to the above treatment protocol from the first day of the cycle until the day of starting progesterone.

(control): estradiol valerate 2 mg. in form of (Cycloprogynova® Bayer Shering Pharma) whitepills starting dose is one pill T.I.D

Study summary

The aim of this work was to investigate the effect of different vasodilators as pentoxifylline in women with unexplained infertility using IVF

Eligibility

Sex

FEMALE

Min age

18 Years

Max age

43 Years

Healthy volunteers

Inclusion Criteria: * as good quality day five frozen embryos. Exclusion Criteria: * history of endocrine diseases, * history of any previous surgery that couldm compromise the integrity of endometrium, * cardiovascular, renal and liver diseases,

Primary outcome measure(s)

Pregnancy — 1 month
Beta-Human Chorionic Gonadotropin (β-hCG) was positive

Trial sites (1)

Facility	City	Region	Status
Beni-suef university Hospital	Banī Suwayf	Beni Suweif Governorate	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07499817 on ClinicalTrials.gov ↗ ← All trials in Egypt