Effect of Tadalafil on Endometrial Thickness and Frozen Embryo Transfer Outcomes

NCT07499804 · tracked via the Priya Life Science Egypt tracker

Sponsor

Beni-Suef University

Phase

Phase 4

Started

2023-10-01

Last updated

2026-03-30

Condition(s) studied

IVFInfertility, Female

Investigational drug(s) / intervention(s)

Tadalafil 5mg →estradiol valerate 2 mg →

Tadalafil 5mg: phosphodiesterase type 5 (PDE-5) inhibitor

estradiol valerate 2 mg: estradiol valerate 2 mg. in form of (Cycloprogynova® Bayer Shering Pharma) white pills starting dose is one pill T.I.D may be increased to two pills T.I.D according to endometrial thickness in day 9 measured by vaginal ultrasound.

Study summary

investigate the effect of different vasodilators as Tadalafil in women with unexplained infertility using IVF

Eligibility

Sex

FEMALE

Min age

18 Years

Max age

43 Years

Healthy volunteers

Inclusion Criteria: * has good quality day five frozen embryos. Exclusion Criteria: * hypotension (blood pressure less than 90/50) and * history of stroke or myocardial infarction

Primary outcome measure(s)

pregnancy — 1 month
whom Beta-Human Chorionic Gonadotropin (β-hCG) was positive

Trial sites (1)

Facility	City	Region	Status
Beni-suef university Hospital	Banī Suwayf	Beni Suweif Governorate	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07499804 on ClinicalTrials.gov ↗ ← All trials in Egypt