Neutrophil to Lymphocyte Ratio in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Condition(s) studied

Investigational drug(s) / intervention(s)

neutrophil lymphocyte ratio in COPD patients: Neutrophil lymphocyte ratio in determining severity and prognosis in exacerbation of COPD patients

Study summary

Chronic obstructive pulmonary disease (COPD) stands as one of the leading causes of mortality worldwide. Acute exacerbations of COPD (AECOPD) lead to rapid respiratory function decline and worsened disease status. Despite recent studies, the ability of the neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in patients with COPD remains controversial. It remains controversial whether NLR can predict clinical outcomes in hospitalized patients with AECOPD. Therefore, this study was conducted to investigate the predictive value of NLR for severity, adverse outcomes in hospitalized patients with AECOPD, and predicting treatment response in patients with AECOPD

Eligibility

Primary outcome measure(s)

• The ratio of neutrophils to lymphocytes in (%) in the CBC — baseline
  investigate the relation between this % ratio and severity of symptoms and adverse hospitalization outcomes in hospitalized patients with AECOPD

Trial sites (1)

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