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Clinical Trials in Egypt / NCT07082361
Starting soon Not applicable

The Use of Diaphragmatic Ultrasonography in Mechanical Ventilation Weaning Decision in COPD Patient

NCT07082361 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2025-10-30
Last updated
2025-07-24

Condition(s) studied

UltrasonographyMechanical Ventilation WeaningChronic Obstructive Pulmonary Disease (COPD)

Investigational drug(s) / intervention(s)

conventional clinical criteria of weaning from mechanical ventilationconventional clinical criteria and ultrasonic criteria for weaning

conventional clinical criteria of weaning from mechanical ventilation: Patients will be weaned after fulfilling the conventional clinical criteria of weaning from mechanical ventilation by using spontaneous breathing trials

conventional clinical criteria and ultrasonic criteria for weaning: Patients will be weaned using the conventional clinical criteria and ultrasonic criteria for weaning.

Study summary

The aim of this study is to evaluate the use of diaphragmatic ultrasonography in taking mechanical ventilation weaning decision and predicting outcome in Chronic obstructive pulmonary disease patient.

Primary outcome:

• Number of patients with failed weaning trial and need reintubation.

Secondary outcomes:

* Time till extubation trial.
* Ventilation free days after extubation less or more than 48h .
* Number of Intensive care unit discharges.
* Sensitivity and specificity of diaphragmatic assessment as a predictor of weaning.

Eligibility

Sex
ALL
Min age
21 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: * Adult patient more than 21 years old of both sexes, coming to our intensive care unit with acute exacerbation of Chronic obstructive pulmonary disease \& need mechanical ventilation at least 48 hr. Exclusion Criteria: * Patient refusal. * Morbid obesity with body mass index \> 35 kg/m2. * Patients with a history of recent thoracic surgery. * Neuromuscular disorders affecting the diaphragm e.g.(myopathy). * Congenital diaphragmatic disorders (Hiatal hernia).

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Tanta University Tanta Gharbia Governorate

More Tanta University trials in Egypt

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07082361 on ClinicalTrials.gov ↗ ← All trials in Egypt