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Clinical Trials in Egypt / NCT06783764
Active, not recruiting Phase 4

Comparative Study Between Combined Modified Pectoral Nerve Block (PECSΙΙ) and Transversus Thoracic Plane Block Versus Erector Spinae Plane Block for Post-operative Analgesia Following Breast Surgeries, (randomized Clinical Trial Study)

NCT06783764 · tracked via the Priya Life Science Egypt tracker
Phase
Phase 4
Started
2024-05-01
Last updated
2025-01-20

Condition(s) studied

Post Operative AnalgesiaPost Operative Pain

Investigational drug(s) / intervention(s)

PECS II block and transverse thoracic plane blockErector Spinae Plane Blockbupivacaine 0.25 % injection →bupivacaine 0.25 % injection →

PECS II block and transverse thoracic plane block: will receive a combination of PECS II block and TTPB (injection of 10 ml 0.25% bupivacaine between pectoralis major and minor muscles and 10 ml between the pectoralis minor and serratus anterior muscles) at the third or the fourth rib, then 10 ml between the internal inter-costal muscles and the transversus thoracic muscle

Erector Spinae Plane Block: ESPB (30 ml of 0.25% bupivacaine injected deep to the erector spinae muscle at the transverse process of the fifth thoracic vertebrae)

bupivacaine 0.25 % injection: injection of 10 ml 0.25% bupivacaine between pectoralis major and minor muscles and 10 ml between the pectoralis minor and serratus anterior muscles) at the third or the fourth rib, then 10 ml between the internal inter-costal muscles and the transversus thoracic muscle

bupivacaine 0.25 % injection: 30 ml of 0.25% bupivacaine injected deep to the erector spinae muscle at the transverse process of the fifth thoracic vertebrae

Study summary

The aim of this study is to compare the analgesic effect and safety of Modified Pectoral Nerve Block and Transverse thoracic plane block versus Erector Supine plane Block in cases undergoing modified radical mastectomy (MRM).

Eligibility

Sex
FEMALE
Min age
25 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Age 25-65 years. * BMI 18-35. * American Society of Anesthesiologists(ASA) Physical Status Class-I, II and III Scheduled for breast surgery Exclusion Criteria: * \- Refusal to give written informed consent. * History of allergy to the medications used in the study. * Contraindications to regional anesthesia (including coagulopathy -INR\>1.6, PLT\<50 × 10\^3/cmm- and local infection). * Psychiatric disorder that leading to inability to cooperate, speak or read. * BMI more than 35. * Patients on medications for chronic pain. * Previous anterior chest wall surgery.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Ain Shams University Cairo Abbasia

More Ain Shams University trials in Egypt

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06783764 on ClinicalTrials.gov ↗ ← All trials in Egypt