This study aims to investigate whether biomarkers of Alzheimer's disease can be found in tearfluid, as well as dried bloodspots in patients with Alzheimer's disease, other dementia diagnoses compared to controls.
Eligibility
Sex
ALL
Min age
30 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
Inclusion criteria for patients:
* Lumbar puncture with CSF avaiable for analysis
* Diagnosis of Alzheimer's disease, Dementia with Lewy Bodies (DLB), Frontotemporal dementia (FTD), vascular dementia (VaD) or Normal pressure hydrocephalus (NPH)
* Of legal age.
Inclusion criteria for controls:
* Lumbar puncture with CSF avaiable for analysis
* No neurological disease.
* Of legal age.
Exclusion Criteria:
* No lumbar puncture
* Clinically assessed as unfit to participate in the project.
Primary outcome measure(s)
AD related biomarkers in tear fluid — Two years Concentrations of AD biomarkers (AB42, AB40, Ptau217, NfL, GFAP) in tear fluid in the AD-group compared to non-AD and controls.
AD related biomarkers in dry blod spots — Two years Concentrations of AD biomarkers (AB42, AB40, Ptau217, NfL, GFAP) in dry blot spots in the AD-group compared to non-AD and controls.
Trial sites (1)
Facility
City
Region
Status
Danish Dementia Research Centre
Copenhagen
Denmark
Recruiting
More Danish Dementia Research Centre trials in Denmark
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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