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Clinical trial register · China

Clinical Trials in Shanghai

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 19052 matching records held by the registry are in this view. Synced 22 Sep 2026, 11:10 UTC
19052
Studies in scope
all four open statuses
11786
Recruiting now
open to new participants
2009
Lead sponsors
across recruiting studies
Top sites
Shanghai 163 Guangzhou 7 Nanjing 5 Harbin 4 Suzhou 4
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Recruitment status
Phase
Lead sponsor
Fudan University454 Ruijin Hospital276 Shanghai Zhongshan Hospital163 RenJi Hospital135 Children's Hospital of Fudan University84 Clear sponsor filter
Site location
Shanghai163 Guangzhou7 Nanjing5 Harbin4 Suzhou4
All 40 locations
Target enrolment
to
163 of 19052 studies
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Status
Study
Lead sponsor
Phase
Enrol
Chinese sites
Start
Recruiting
Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer
NCT06468280Gastric Cancer, GastroEsophageal Cancer
Shanghai Zhongshan Hospital
Phase 2
84
Shanghai
2024-11-08
Recruiting
Differential Study of Invasive Pituitary Adenomas in the Sellar and Cavernous Sinus Regions
NCT06705036Pituitary Tumor
Shanghai Zhongshan Hospital
Observational
20
Shanghai
2024-11-01
Not yet open
Therapeutic Effects of Immuno-targeted Therapy Combined With or Without RT for HCC
NCT06639971Hepatocellular Carcinoma (HCC)
Shanghai Zhongshan Hospital
Observational
500
Shanghai
2024-11-01
Recruiting
A Prospective Multicenter Clinical Study๏ผš IntracOronary neaR-Infrared Spectroscopy and OptIcal Coherence Tomography for Evaluating Coronary vulNerable Plaque in Patients With diabeTes
NCT06649305Coronary Heart Disease (CHD), Diabetes (DM)
Shanghai Zhongshan Hospital
Observational
1,516
Shanghai
2024-10-30
Recruiting
Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCC
NCT06637163Esophageal Squamous Cell Carcinoma
Shanghai Zhongshan Hospital
Phase 2
100
Shantou, Shenyang, Shanghai, Tianjin, Hangzhou
2024-10-24
Recruiting
Profile and Regulatory Network of Exercise in Improving Metabolic Phenotypes of Patients With Prediabetes
NCT06633575Prediabetes
Shanghai Zhongshan Hospital
Not applicable
40
Shanghai
2024-10-12
By invitation
Retrospective Study on Leptomeningeal Metastasis of Solid Tumors
NCT06705049Leptomeningeal Metastasis
Shanghai Zhongshan Hospital
Observational
107
Shanghai
2024-10-01
Not yet open
a Foundational Model for Cardiovascular Disease Diagnosis and Prediction
NCT06591923Coronary Heart Disease (CHD), Heart Failure, Arrhythmias, Valvular Heart Disease
Shanghai Zhongshan Hospital
Observational
1,000,000
Shanghai
2024-10
Not yet open
Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC
NCT06599827Rectal Cancer
Shanghai Zhongshan Hospital
Phase 2
54
Shanghai
2024-09-20
Recruiting
Anti-PD-1/PD-L1 Antibodies Plus Anti-VEGF Antibody Treatment in Patients With Advanced-Stage HCC
NCT06537908Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
Observational
50
Shanghai
2024-08-01
Active, closed
A Real-world Study to Evaluate the Effectiveness of Intravascular Lithotripsy in Moderate to Severe Calcification Lesion of Lower Extremity Femoropopliteal Artery
NCT06636968Peripheral Arterial Disease
Shanghai Zhongshan Hospital
Observational
200
Shanghai
2024-07-31
Recruiting
The Efficacy and Safety of LM-302 in Combination With Candonilimab and Capecitabine for First-Line Treatment in Patients With Unresectable Advanced, Recurrent, or Metastatic CLDN18.2-Positive Gastric or Gastroesophageal Junction Adenocarcinoma
NCT06587425Gastric or Gastroesophageal Junction Adenocarcinoma
Shanghai Zhongshan Hospital
Phase 2
50
Shanghai
2024-07-31
Recruiting
Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA
NCT07291063Cholangiocarcinoma
Shanghai Zhongshan Hospital
Observational
50
Shanghai
2024-07-19
Not yet open
Remimazolam Besylate and Propofol Sedation on Hemodynamic for Coronary Artery Bypass Graft Patients
NCT06496165Coronary Artery Disease
Shanghai Zhongshan Hospital
Not applicable
338
Shanghai
2024-07-15
Recruiting
FeNO Observation Study in ICU Patients With ARS
NCT06680895Compare the Concentration of Exhaled Nitric Oxide in Patients With Different Severity of RF
Shanghai Zhongshan Hospital
Observational
1,000
Shanghai
2024-07-01
Not yet open
Predicting Adverse Kidney Events of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers
NCT06351813Acute Kidney Injury, Critical Illness, Kidney Failure
Shanghai Zhongshan Hospital
Observational
358
Shanghai
2024-07-01
Not yet open
Combining Chemoradiotherapy With Sintilimab in First-Line ICC
NCT06447454ICC
Shanghai Zhongshan Hospital
Observational
19
Shanghai
2024-07-01
Not yet open
Consolidative Radiotherapy (CSRT) in Patients With Oligometastatic/Locally Advanced Unresectable Bilary Tract Cancer (BTC)
NCT06502080Biliary Tract Cancer
Shanghai Zhongshan Hospital
Phase 2
128
Shanghai
2024-07
Recruiting
A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's Arteritis
NCT06498089Takayasu Arteritis
Shanghai Zhongshan Hospital
Phase 4
124
Shanghai
2024-06-28
Recruiting
Impact of External Drainage of the Main Pancreatic Duct and Common Bile Duct on Pancreatic Fistula Following Pancreaticoduodenectomy
NCT06322680Pancreaticoduodenectomy
Shanghai Zhongshan Hospital
Not applicable
322
Shanghai
2024-05-24
Recruiting
Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy
NCT06382103Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
Observational
240
Shanghai
2024-05-15
Recruiting
IVUS CHIP China Registry
NCT06274645Complex Higher Risk Indicated Patients Undergoing PCI
Shanghai Zhongshan Hospital
Observational
2,020
Shanghai
2024-03-12
Recruiting
Delirium Phenotypes and Subsequent Impairment During Transition From ICU to Hospital Wards
NCT07193797Delirium, Post ICU Syndrome
Shanghai Zhongshan Hospital
Observational
189
Shanghai
2024-03-01
Recruiting
Carotid Atherosclerosis in Predicting Coronary Artery Disease
NCT06253962Carotid Atherosclerosis, Coronary Atheroscleroses
Shanghai Zhongshan Hospital
Observational
1,000
Shanghai
2024-02-10
By invitation
Efficacy of Vitamin B1 in Familial Adenomatous Polyposis Patients.
NCT06649825Familial Adenomatous Polyposis (FAP)
Shanghai Zhongshan Hospital
Not applicable
10
Shanghai
2024-01-08
Not yet open
Second-line Zimberelimab and SIRIOX Chemotherapy for Patient With Previously AG Chemotherapy Treated Pancreatic Cancer
NCT06166589Previously AG Chemotherapy Treated Pancreatic Cancer
Shanghai Zhongshan Hospital
Phase 2
19
Shanghai
2024-01-01
Recruiting
Efficacy and Safety of Neoadjuvant Envafolimab Combined With Albumin-bound Paclitaxel and Carboplatin for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma
NCT07266493Esophageal Squamous Cell Carcinoma, Neoadjuvant Therapy
Shanghai Zhongshan Hospital
Phase 2
26
Shanghai
2023-12-01
By invitation
Potential Biomarkers and Pathogenic Mechanism for Reflux Aspiration-induced Lung Injury.
NCT06164639ARDS, Human, Aspiration Pneumonia
Shanghai Zhongshan Hospital
Observational
28
Shanghai
2023-11-28
Recruiting
The Effect of Continuous Intravenous Infusion of Lidocaine on PPCs and Prognosis in Emergency Surgical Patients With IAI
NCT06304779Postoperative Pulmonary Complications, Intra-abdominal Infection
Shanghai Zhongshan Hospital
Not applicable
428
Shanghai
2023-10-31
Recruiting
Study of Furmonertinib as Neoadjuvant Therapy for Resectable Stage โ…ก-โ…ขB EGFR Sensitive Mutant NSCLC
NCT05987826Non-Small Cell Lung Cancer
Shanghai Zhongshan Hospital
Phase 2
40
Shanghai
2023-09-19
Recruiting
FreeFlow Percutaneous Atrial Septal Shunt for IPAH
NCT06605794Pulmonary Arterial Hypertension
Shanghai Zhongshan Hospital
Not applicable
30
Shanghai
2023-09-11
Active, closed
Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standard of Chemotherapy and PD1/PD-L1 Antibody
NCT05994001Biliary Tract Cancer, Candonilimab, Claudin 18.2
Shanghai Zhongshan Hospital
Phase 1/2
78
Shanghai
2023-08-01
Recruiting
The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The CHAPERONE Study
NCT05965115Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance
Shanghai Zhongshan Hospital
Observational
10,000
Shanghai
2023-07
Recruiting
Efficacy and Safety Evaluation of Fecal Microbiota Transplantation in Irritable Bowel Syndrome
NCT05740319Irritable Bowel Syndrome
Shanghai Zhongshan Hospital
Not applicable
102
Shanghai
2023-06-10
Recruiting
The Pathogenesis and Prognostic Factors of Lymphoma
NCT06203652Lymphoma, Hodgkin Lymphoma, Non-hodgkin Lymphoma
Shanghai Zhongshan Hospital
Observational
2,000
Shanghai
2023-06-05
Recruiting
Consistency of Carotid Doppler Blood Flow and Thermodilution Technique
NCT05944146Cardiac Surgery
Shanghai Zhongshan Hospital
Not applicable
200
Shanghai
2023-05-31
Not yet open
Clinical Outcomes of CT-FFR Versus QFR-guided Strategy for Decision-Making in Patients With Stable Chest Pain
NCT05857904Angina, Stable, Coronary Artery Disease
Shanghai Zhongshan Hospital
Not applicable
4,648
Shanghai
2023-05
Recruiting
Longitudinal Data Registry of Plasma Cell Dyscrasia
NCT06760052Multiple Myeloma and Other Plasma Cell Neoplasms
Shanghai Zhongshan Hospital
Observational
2,000
Shanghai
2023-03-01
Recruiting
A Randomized Controlled Trial Comparing Clinical Effectiveness of SMILE Versus SMILE Xtra in Myopia
NCT06992011Myopia
Shanghai Zhongshan Hospital
Not applicable
300
Shanghai
2023-02-01
Recruiting
A Prospective Study on Clinical Effectiveness After SMILE Versus SMILE Xtra in Myopia
NCT06973278Myopia
Shanghai Zhongshan Hospital
Not applicable
200
Shanghai
2023-02-01
Recruiting
Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma
NCT05563922Rectal Cancer
Shanghai Zhongshan Hospital
Phase 2
56
Shanghai
2022-09-01
Recruiting
A Prospective Observation Registry Study on the Alimentary Reconstruction After Radical Proximal Gastrectomy
NCT05539105Proximal Gastric Adenocarcinoma, Reconstruction
Shanghai Zhongshan Hospital
Observational
600
Shanghai
2022-08-22
Recruiting
Efficacy and Safety of Radiotherapy in Oligoprogressive HCC Following First-line PD-1 Therapy
NCT06870942HCC - Hepatocellular Carcinoma, Radiotherapy
Shanghai Zhongshan Hospital
Phase 2
35
Shanghai
2022-07-28
Not yet open
Two-field Versus Three-field Lymph Node Dissection in ESCC After Neoadjuvant Therapy
NCT05420480Esophageal Squamous Cell Carcinoma
Shanghai Zhongshan Hospital
Not applicable
323
Shanghai
2022-07-01
Active, closed
Impact of Partial Capsule Decortication on Device-related Infection in Patients Receiving Cardiac Implantable Electronic Device Replacement
NCT05390216Pacemaker Complication, Infections
Shanghai Zhongshan Hospital
Not applicable
1,016
Shanghai
2022-06-05
Recruiting
Neoadjuvant Immunotherapy Plus CRT Versus Neoadjuvant CRT for Locally Advanced Resectable ESCC
NCT04973306Esophageal Squamous Cell Carcinoma Stage II, Esophageal Squamous Cell Carcinoma Stage III
Shanghai Zhongshan Hospital
Phase 2/3
176
Shanghai
2022-03-02
Recruiting
Detection of Peritoneal Metastasis of Gastric Cancer by Liquid Biopsy in Peripheral Blood: A Prospective Study
NCT05347524Cancer
Shanghai Zhongshan Hospital
Observational
384
Shanghai
2022-03-01
Active, closed
Effectiveness of Treatments for Cirrhosis With Varicose Veins
NCT06961474Esophageal Varices Bleeding, Portal Hypertension
Shanghai Zhongshan Hospital
Observational
1,900
Shanghai
2022-02-01
Not yet open
Prospective Acute Myocardial Infarction Data Bank
NCT05121818Acute Myocardial Infarction
Shanghai Zhongshan Hospital
Observational
3,000
Shanghai
2022-01-01
Recruiting
Comparison of Tofacitinib and Methotrexate in Takayasu's Arteritis
NCT05102448Takayasu Arteritis
Shanghai Zhongshan Hospital
Phase 4
76
Shanghai
2021-11-01
Recruiting
This Study is a Prospective, Multi-center, Real World, Observational Study, Which Aims at Evaluating Intermediate and Long-term Efficacy of Endovascular Treatment for TASC C&D Aortoiliac Occlusive Disease.
NCT05391815Peripheral Arterial Disease
Shanghai Zhongshan Hospital
Observational
800
Shanghai
2021-04-01
Active, closed
PD-L1 Antibody Combined With CTLA-4 Antibody for Patients With Advanced Intrahepatic Cholangiocarcinoma Who Progressed After Standard Treatment
NCT04634058Cholangiocarcinoma, Intrahepatic, PD-L1, CTLA4
Shanghai Zhongshan Hospital
Phase 2
40
Shanghai
2021-03-26
Active, closed
Camrelizumab Combined With Apatinib Mesylate for Perioperative Treatment of Resectable Hepatocellular Carcinoma
NCT04521153Hepatocellular Carcinoma, Immunotherapy, Molecular Targeted Therapy
Shanghai Zhongshan Hospital
Phase 2/3
294
Shanghai
2021-03-25
Active, closed
Phase II-III Clinical Trial of PD1 Antibody (Toripalimab), Lenvatinib and GEMOX Neoadjuvant Treatment for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors
NCT04669496Intrahepatic Cholangiocarcinoma, PD1 Antibody, Lenvatinib, Gemox Chemotherapy
Shanghai Zhongshan Hospital
Phase 2/3
178
Shanghai
2021-01-20
Recruiting
Multicenter Study on Laparoscopic Total Gastrectomy for Advanced Gastric Cancer
NCT04710758Stomach Neoplasms
Shanghai Zhongshan Hospital
Not applicable
1,018
Shanghai
2021-01-20
Recruiting
A Prospective, Two-center, Single Arm Phase II Clinical Study to Evaluate Safety and Effectiveness of Ablation Therapy in the Treatment of Lung Cancer Presenting as Ground-glass Nodules
NCT04905056Progression
Shanghai Zhongshan Hospital
Phase 2
120
Shanghai
2021-01-01
Recruiting
Neoadjuvant Anti-PD-1 Plus Chemotherapy in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma
NCT05740995Esophageal Squamous Cell Carcinoma, Neoadjuvant Chemoimmunotherapy
Shanghai Zhongshan Hospital
Observational
40
Shanghai
2020-12-01
Recruiting
A Multiple-center Study on the Effect of Different Ways of Lymph Node Dissection on the Prognosis of Ground Glass Nodules Smaller Than 3cm and With More Than 50% Solid Components
NCT04581122Progression
Shanghai Zhongshan Hospital
Not applicable
1,500
Shanghai
2020-09-01
Active, closed
PD-1 Antibody (SHR-1210) Plus Capecitabine in Patients with Intrahepatic Cholangiocarcinoma After Surgery
NCT04295317Intrahepatic Cholangiocarcinoma
Shanghai Zhongshan Hospital
Phase 2
65
Shanghai
2020-08-01
Recruiting
A Pilot Study in Severe Patients With Takayasu Arteritis.
NCT04300686Takayasu Arteritis, Tocilizumab, Adalimumab, Treatment
Shanghai Zhongshan Hospital
Phase 4
40
Shanghai
2020-03-01
Recruiting
Indicators Affecting PVT Recanalization
NCT07473375Portal Vein Thrombosis, Cirrhosis, Portal Hypertension Related to Cirrhosis, Portal Hypertension, Noncirrhotic
Shanghai Zhongshan Hospital
Observational
1,500
Shanghai
2017-01-01
Recruiting
CHART Study of Coronary CT Angiography in Coronary Artery Disease
NCT05380622Coronary Artery Disease
Shanghai Zhongshan Hospital
Observational
5,000
Shanghai
2015-01-01
Not yet open
PEG-rhGH and Semaglutide Combination Therapy in Non-Diabetic Obese Adults
NCT06863363Non-diabetic Obesity
Shanghai Zhongshan Hospital
Phase 4
212
Shanghai
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Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 22 September 2026. https://priyalifescience.com/clinical-trials-china/city/shanghai?page=2

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