University of Electronic Science and Technology of China
Phase
Not applicable
Started
2026-09-05
Last updated
2026-09-11
Condition(s) studied
Healthy Adult Participants
Investigational drug(s) / intervention(s)
Oxytocin nasal sprayPlacebo
Oxytocin nasal spray: intranasal administration of oxytocin (24IU)
Placebo: intranasal administration of placebo (24IU)
Study summary
This study aims to investigate the modulation of intranasally administered oxytocin (24 IU) on human fairness perception and related prosocial behaviors.
Eligibility
Sex
ALL
Min age
18 Years
Max age
35 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Healthy subjects without past or current psychiatric or neurological disorders.
Exclusion Criteria:
* History of head injury; pregnant, menstruating, taking oral contraceptives; medical or psychiatric illness.
* The presence of metal in the body or claustrophobia.
Primary outcome measure(s)
Fairness rating scores — 1 hour Participants are asked to rate their perceived levels of fairness on a 9-point Likert scale (1 = highly fair, 9 = highly unfair) to the computer's allocation in each trial.
Anticipated guilt rating scores — 1 hour Participants are asked to rate the anticipated guilt they would feel if they accepted the allocation given by the computer in each trial. Ratings were conducted on a 9-point Likert scale (1 = not at all, 9 = highly guilty).
The binary decision to the initial allocation — 1 hour Participants are asked to makde decisions of accepting or rejecting the allocation provided by the computer in each trial.
Brain activity patterns — 1 hour Brain activity patterns in response to the outcome of the allocation given by computer and the binary decision. We will examine these brain response patterns via both the conventional univariate analysis and the machine learning-based multivariate pattern analysis (MVPA) approaches.
Trial sites (1)
Facility
City
Region
Status
University of Electronic Science and Technology of China (UESTC)
Chengdu
Sichuan
Recruiting
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