Continuous vs. Intermittent Rt-fMRI Neurofeedback Training of the Anterior Insula

NCT07389486 · tracked via the Priya Life Science China tracker

Sponsor

University of Electronic Science and Technology of China

Phase

Not applicable

Started

2026-01-28

Last updated

2026-02-05

Condition(s) studied

Healthy

Investigational drug(s) / intervention(s)

real-time fMRI neurofeedback training procedurereal-time fMRI sham-controlled neurofeedback training procedurereal-time fMRI neurofeedback training procedure

real-time fMRI neurofeedback training procedure: real-time fMRI neurofeedback training procedure running on the Turbo Brain voyager (TBV) 4.2 software (Brain Innovation, Maastricht, The Netherlands)

real-time fMRI sham-controlled neurofeedback training procedure: real-time fMRI sham neurofeedback training procedure running on the Turbo Brain voyager (TBV) 4.2 software (Brain Innovation, Maastricht, The Netherlands)

Study summary

The main aim of this study is to compare the efficacy of intermittent with continuous real-time functional magnetic resonance imaging (fMRI) neurofeedback on anterior insula regulation and associated behavioral changes.

Eligibility

Sex

ALL

Min age

18 Years

Max age

30 Years

Healthy volunteers

Accepted

Inclusion Criteria: Healthy subjects without any past or present psychiatric or neurological disorders Exclusion Criteria: History of brain injury medical or mental illness Contraindication to MRI scanning (e.g., metal implants, claustrophobia or other --conditions that make them inappropriate for MRI scanning)

Primary outcome measure(s)

Neural activity of the anterior insula based on blood oxygen level-dependent (BOLD) signal — 1 hour
The anterior insula activity induced during the regulation block compared to the baseline block.
Pain empathy ratings scores — 1 hour
Subjects were required to rate their empathic feeling towards painful pictures on a Likert Scale ranging from 1-9 (1 = not at all and 9 = very painful) before and after neurofeedback training.

Trial sites (1)

Facility	City	Region	Status
University of Electronic Science and Technology of China	Chengdu	Sichuan	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07389486 on ClinicalTrials.gov ↗ ← All trials in China