Individual Differences in Cognitive Control Predict Real-time fMRI Neurofeedback Performance

Condition(s) studied

Investigational drug(s) / intervention(s)

Real-time fMRI neurofeedback training: Real-time neurofeedback information is computed using the Turbo Brain voyager (TBV) 4.0 software (Brain Innovation, Maastricht, The Netherlands). Functional images are collected and processed in real time based on contrasts of regulation vs. rest conditions. The BOLD signal of the target region is then transformed into visual bars and displayed to participants via the projector screen while participants keep using regulation strategy (heartbeat interoception in our study) to upregulate the target region.

Study summary

The goal of this study is to investgate whether individual differences of cognitive control capacity could predict neurofeedback performance and the behavioral effects resulting from successful anterior insula regulation via interoceptive strategy.

Eligibility

Primary outcome measure(s)

• BOLD signal of the anterior insula during neurofeedback training — 1 hour
  The anterior insula activity induced by regulation relative to rest blocks in the neurofeedback training task and transfer task.
• Behavioral measurements in the cognitive control tasks — 1 hour
  Response time and accuracy are recorded in the cognitive control tasks (i.e., the Go/No-Go task, Stroop task, Task-switching, N-back task).

Trial sites (1)

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