Eccentric resistance exercise: 150 maximal, unilateral eccentric contractions of the quadriceps muscles on a computerized dynamometer.
Study summary
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS). DOMS is characterized by muscle pain and tenderness that typically resolves within a week. While the precise cause of DOMS is unknown, there is growing evidence implicating damage to the connective tissue that surrounds our muscle fibers and is related to a small amount of inflammation. This inflammation is a normal part of our body's ability to recovery from injuries and may be visualized through the use of ultrasound technology. A variety of recovery techniques have been proposed that may help with the recovery of DOMS such as massage and electrical muscle stimulation, but these are not always accessible. Therefore, we are interested in investigating whether the number of daily steps can affect how you experience DOMS.
Eligibility
Sex
ALL
Min age
18 Years
Max age
35 Years
Healthy volunteers
Accepted
Inclusion Criteria:
\- Healthy, recreationally active male and female participants (i.e., weekly MET-minutes \> 3000 assessed by International Physical Activity Questionnaire).
Not having a health condition that would compromise their ability to safely participate in the strenuous physical activity involved in our study screened for by the get active questionnaire.
Between 18 and 35 years old.
Body mass index (BMI) between 18.5-30
Self-reported not having engaged in resistance exercise and/or lower body plyometrics for at least 3 months prior to the study.
Willing to abide by the compliance rules of this study.
Self-reported regular menstrual cycle (25-35d) within the last 3 months (female participants).
Exclusion Criteria:
Inability to adhere to any of the compliance rules judged by the principal investigator or medical doctor.
Self-reported regular tobacco use.
Regular use of non-steroidal anti-inflammatory drugs (e.g., Advil)
Use of oral contraceptives (female participants).
Primary outcome measure(s)
Change in maximal muscle strength between physical activity levels — Daily assessment (every 24 hours) across 96 hours post-exercise Maximal voluntary isometric and isokinetic contraction assessed by peak torque via computerized dynamometer.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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