3 whole eggs: Participants will be free-living and will not be supplied with any other food except for the eggs during the intervention period with no restrictions of energy intake.
Study summary
The purpose of this research is to determine the effect of additional daily egg intake on metabolic phenotypes and metabolism in the context of obesity.
Eligibility
Sex
ALL
Min age
30 Years
Max age
65 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Male or female participant of any race or ethnicity between 30-65 (inclusive) years of age
* BMI \> 30 kg/m2
* Non-smoker
* Willing to consume 3 eggs per day for one dietary period of 4 weeks
* Willing to avoid eggs during the rest of the study except for eggs that are provided
* Willing to follow the study protocol including maintaining usual lifestyle during the entire study
Exclusion Criteria:
* Age \< 30 or \> 65 years
* BMI \< 30 kg/m2
* Vegans or individuals who do not consume eggs
* Individuals who are currently pregnant or planning to become pregnant during the course of the study; or are currently breastfeeding
* Smokers, users of recreational drugs
* Individuals taking antibiotics or natural health products including prebiotics or probiotics
Primary outcome measure(s)
Liver physical density by imaging technologies — Weeks 0, 4, 8 and 12
Liver morphology as assessed by imaging technologies — Weeks 0, 4, 8 and 12
Concentration of circulating liver enzymes — Weeks 0, 4, 8 and 12
Concentration of circulating lipid markers — Weeks 0, 4, 8 and 12
Concentration of circulating glucose markers — Weeks 0, 4, 8 and 12
Body mass index in kg/m^2 — Weeks 0, 4, 8 and 12
Body circumference in metrics — Weeks 0, 4, 8 and 12
Trial sites (1)
Facility
City
Region
Status
Research Center of the Institut universitaire de cardiologie et de pneumologie de Québec - ULaval
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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