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Clinical Trials in Canada / NCT06356948
Recruiting Phase 4

Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.

NCT06356948 · tracked via the Priya Life Science Canada tracker
Phase
Phase 4
Started
2024-03-30
Last updated
2024-04-10

Condition(s) studied

Healthy Participants

Investigational drug(s) / intervention(s)

Tranexamic Acid (TXA) →

Tranexamic Acid (TXA): Study drug administration

Study summary

Tranexamic acid is a well-established treatment for post-partum hemorrhage. This study aims to examine the effect of tranexamic acid administration rates on blood pressure changes over 1 minute compared to 10 minutes in healthy pregnant patients scheduled for cesarean delivery.

Eligibility

Sex
FEMALE
Min age
19 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Pregnant patients ≥34 weeks gestational age, for elective cesarean delivery under single-shot spinal anesthesia. * American Society of Anesthesiologists (ASA) Physical Status Class 2. * Patients ≥19 years of age. Exclusion Criteria: * Known history of pre-existing hypertension or hypertension disorders of pregnancy. * Having recently taken a medication to treat high blood pressure (e.g. labetolol, hydralazine, nifedipine) * Having recently taken a medication that could alter blood pressure, which could include beta those prescribed for anxiety (e.g. propranolol) or sedative pre-medication (e.g. midazolam, lorazepam). * Known allergic reaction or hypersensitivity to TXA or any other TXA homologue. * Elective cesarean delivery requiring general anesthesia or a neuraxial technique other than a single-shot spinal (e.g. Epidural or Combined Spinal Epidural). * Patients who are unable to give informed consent due to a language barrier as the study team only speaks English and will be unable to complete consent process and study procedure appropriately. * Patients arriving late to the surgical day care with \<90 min prior to scheduled cesarean delivery time resulting in potential delay for the operating room or inadequate time for consent and full execution of the protocol.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
BC Women's Hospital Vancouver British Columbia Recruiting

More University of British Columbia trials in Canada

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06356948 on ClinicalTrials.gov ↗ ← All trials in Canada