Austrian PBC Registry

NCT07598669 · tracked via the Priya Life Science Austria tracker

Sponsor

Medical University of Vienna

Phase

Observational

Started

2026-03-18

Last updated

2026-05-20

Condition(s) studied

Primary Biliary CholangitisLiver CirrhosisPortal Hypertension

Study summary

The goal of this registry is to better understand how primary biliary cholangitis develops over time, including the role of disease-related biomarkers, complications of the disease, and symptom burden. Patients with primary biliary cholangitis treated at participating centres in Austria will be invited to take part in this prospective registry. Participation in an associated biobank is optional. Clinical and laboratory data will be collected, and patients will be followed regularly through scheduled clinic visits. In addition, biological samples (serum, plasma, and, if available, liver tissue) may be collected and stored in the biobank for future research.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Age \>18 years * Confirmed diagnosis of primary biliary cholangitis (at least two of the following three criteria must be fulfilled: persistent elevation of alkaline phosphatase above the upper limit of normal for at least 6 months; presence of antimitochondrial antibodies or PBC-specific antinuclear antibodies; characteristic histopathology) * Written informed consent for participation in the registry Exclusion Criteria: * Withdrawal of written informed consent

Primary outcome measure(s)

Transplant-free survival — Through study completion, an average of 5 years
Time from inclusion to death or liver transplantation

Trial sites (11)

Facility	City	Region	Status
Klinikum Klagenfurt am Wörthersee	Klagenfurt	Carinthia	Not Yet Recruiting
Universitätsklinikum St. Pölten	Sankt Pölten	Lower Austria	Not Yet Recruiting
Universitätsklinikum Salzburg	Salzburg	State of Salzburg	Not Yet Recruiting
Klinik Landstraße	Vienna	State of Vienna	Not Yet Recruiting
Medizinische Universität Wien	Vienna	State of Vienna	Recruiting
Klinik Ottakring	Vienna	State of Vienna	Not Yet Recruiting
Medizinische Universität Graz	Graz	Styria	Not Yet Recruiting
Medizinische Universität Innsbruck	Innsbruck	Tyrol	Not Yet Recruiting
Ordensklinikum Linz - Barmherzige Schwestern	Linz	Upper Austria	Not Yet Recruiting
Kepler Universitätsklinikum	Linz	Upper Austria	Not Yet Recruiting
Klinikum Wels-Grieskirchen	Wels	Upper Austria	Not Yet Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07598669 on ClinicalTrials.gov ↗ ← All trials in Austria