Statins in Reducing Events in the Elderly (STAREE) Heart Sub-study

NCT04536870 · tracked via the Priya Life Science Australia tracker

Sponsor

Monash University

Phase

Not applicable

Started

2019-12-12

Last updated

2025-04-02

Condition(s) studied

Heart FailureAtrial FibrillationHealthy AgeingHypercholesterolemiaMyocardial Dysfunction

Investigational drug(s) / intervention(s)

EchocardiographyECG screeningECG Screening

Echocardiography: Ultrasound of heart

ECG screening: Single lead ECG screening twice daily for two weeks

ECG Screening: 12-lead ECG screening

Study summary

The STAREE-HEART sub-study will examine the effect of statin treatment over a 3-year period compared with placebo on markers of cardiac ageing (myocardial dysfunction). This will include determining global longitudinal strain with transthoracic echocardiography, atrial fibrillation with home measures twice daily for two weeks and changes in biomarkers.

Eligibility

Sex

ALL

Min age

70 Years

Max age

—

Healthy volunteers

Accepted

Inclusion Criteria: * Men and women aged ≥70 years living independently in the community who are participants in the STAREE RCT and eligible for randomisation to study medication. * Willing and able to provide informed consent and accept the STAREE-HEART study requirements, including attendance for an echocardiogram and undertaking home monitoring via ECG. Exclusion Criteria: * Known atrial fibrillation or atrial flutter. * Participants who do not wish to be informed of an abnormality under any circumstances, regardless of severity, will not be enrolled in the study.

Primary outcome measure(s)

Global longitudinal strain (GLS) measured via transthoracic echocardiography. — 3 years
Change in global longitudinal strain.

Trial sites (2)

Facility	City	Region	Status
Monash University; School of Public Health and Preventative Medicine: STAREE trial	Melbourne	Victoria
Curtin University	Perth	Western Australia

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04536870 on ClinicalTrials.gov ↗ ← All trials in Australia