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Clinical Trials in Australia / NCT02863250
Recruiting Observational

Australian and New Zealand Massive Transfusion Registry

NCT02863250 · tracked via the Priya Life Science Australia tracker
Phase
Observational
Started
2011-03
Last updated
2020-09-02

Condition(s) studied

Massive TransfusionTraumaCardiothoracic SurgeryGastrointestinal BleedingVascular SurgeryObstetric BleedingLiver Transplant

Study summary

Severe and un-stopped blood loss can occur for a number of different reasons including after a serious injury, delivery of a baby and following other medical and surgical emergencies. The investigators understanding of how to best treat people with serious bleeding is still incomplete, with many questions remaining. These include questions regarding how many people have serious bleeding events, what happens to them and the best way to treat them.

The Massive Transfusion Registry (MTR) is a register of patients who have experienced major blood loss that required a massive transfusion in any clinical setting.

The MTR uses electronic data extraction and data linkage methodologies. Pre-existing clinical data from hospital data sources, including Laboratory Information Systems (for transfusion history and laboratory results) and Health Information Services databases (for Patient demographics and admission data), are electronically extracted by staff employed at the participating hospitals. The data is then sent to the MTR Research Team, located at Monash University, where it is then linked, analysed and stored.

The establishment of a Massive Transfusion Registry will be a unique and important resource for clinicians in Australia, New Zealand and internationally, for Blood Services and for the broader community. It will provide valuable observational data regarding the types and frequency of conditions associated with critical bleeding requiring massive transfusion, the use of blood component therapy (i.e. ratios and quantities of different types of red cell to non- red cell components) and patient outcomes.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * aged 18 years or over * 5 or more units of red blood cells in any 4 hour period Exclusion Criteria: * nil

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Monash University Melbourne Victoria Recruiting

More Monash University trials in Australia

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT02863250 on ClinicalTrials.gov ↗ ← All trials in Australia