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Natera clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA register with Natera as lead sponsor. Synced 26 Sep 2026
12Current trials
7Recruiting now
0Drugs in these trials
1Trial register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Natera is the lead sponsor of 12 current clinical trials in our USA register. 7 are recruiting patients now. The most common phase is Observational. The most-studied condition is Kidney Transplant Rejection.

ClinicalTrials.gov trials by status

  • Recruiting758%
  • Not yet open18%
  • Active, closed433%

Trials by phase

  • Observational975%
  • Not applicable325%
01

Clinical trials sponsored by Natera

12 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND)
NCT06808880 · Single Gene NIPT
Observational Recruiting 2024-01 USA
Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin Lymphoma (SCORE-NHL)
NCT07750886 · ClinicalTrials.gov ↗ · Non-Hodgkin Lymphoma, T-Cell Lymphoma, Diffuse Large B-Cell Lymphoma
Observational Recruiting 2026-07 USA
Sample Collection for Ongoing Research and Product Evaluation Study - Non-muscle Invasive Bladder Cancer (SCORE-NMIBC)
NCT07763197 · ClinicalTrials.gov ↗ · Non-Muscle Invasive Bladder Cancer, NMIBC, High-risk Non-Muscle Invasive Bladder Cancer
Observational Recruiting 2026-07 USA
Evaluation of the Natera Colorectal Cancer Screening Test in an Average Risk Population (FIND-CRC)
NCT07046585 · ClinicalTrials.gov ↗ · Colo-rectal Cancer
Observational Recruiting 2025-05 USA
Sample Collection for Ongoing Research and Product Evaluation Study
NCT07318051 · ClinicalTrials.gov ↗ · Breast Cancer, Lung Cancer, Muscle Invasive Bladder Cancer
Observational Recruiting 2025-07 USA
Prospective Collection of Samples to Enable the Development of Natera Screening Assay for Early Cancer Detection
NCT06620627 · ClinicalTrials.gov ↗ · Colorectal Cancer Screening
Observational Recruiting 2024-01 USA
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
NCT07214532 · ClinicalTrials.gov ↗ · Breast Neoplasms, Carcinoma, Ductal, Breast, Receptors, Estrogen (for ER-positive Requirement)
Not applicable Recruiting 2026-05 USA
Signatera Assessment in Early-Stage Endometrial Cancer
NCT07339384 · Endometrial Cancer
Not applicable Not yet open 2026-10 USA
The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
NCT04091984 · Kidney Transplant Rejection
Observational Active, closed 2019-11 USA
A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy
NCT06414603 · Heart Transplant Failure and Rejection
Not applicable Active, closed 2024-06 USA
LAMBDA 002 (Lung Registry) Study
NCT05170425 · ClinicalTrials.gov ↗ · Lung Transplant Rejection
Observational Active, closed 2022-11 USA
Prospera Test Evaluation in Cardiac Transplant (ProTECT)
NCT05205551 · ClinicalTrials.gov ↗ · Heart Transplant Rejection
Observational Active, closed 2021-10 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Conditions in Natera trials

22 conditions
Kidney Transplant Rejection1Heart Transplant Failure and Rejection1Single Gene NIPT1Endometrial Cancer1Lung Transplant Rejection1Non-Hodgkin Lymphoma1T-Cell Lymphoma1Diffuse Large B-Cell Lymphoma1High-Grade B-Cell Lymphoma1Non-Muscle Invasive Bladder Cancer1NMIBC1High-risk Non-Muscle Invasive Bladder Cancer1Colo-rectal Cancer1Heart Transplant Rejection1Breast Cancer1Lung Cancer1Muscle Invasive Bladder Cancer1Rectal Cancer1Colorectal Cancer Screening1Breast Neoplasms1Carcinoma, Ductal, Breast1Receptors, Estrogen (for ER-positive Requirement)1
03

By trial register

RegisterTrialsRecruiting
Clinical trials in USA127

A trial with sites in more than one country appears in each of those registers.

04

Other sponsors in Kidney Transplant Rejection

SponsorTrials
Sangamo Therapeutics1

Sponsors with the most current trials registered for this condition.

05

Questions about Natera trials

How many clinical trials does Natera sponsor?

Natera is the lead sponsor of 12 current trials on ClinicalTrials.gov in our USA register, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Natera trials recruiting?

Yes. 7 of its 12 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.