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Sponsor · clinical trials

BicycleTx clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA, UK, Spain, France, Italy, Belgium, South Korea, Canada, Australia, China, Germany, Poland, Turkey, Brazil, Taiwan, Singapore and Israel registers with BicycleTx as lead sponsor. Synced 27 Sep 2026
7Current trials
1Recruiting now
10Drugs in these trials
17Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

BicycleTx is the lead sponsor of 7 current clinical trials in our USA, UK, Spain, France, Italy, Belgium, South Korea, Canada, Australia, China, Germany, Poland, Turkey, Brazil, Taiwan, Singapore and Israel registers. 1 is recruiting patients now. The most common phase is Phase 2. The drugs named most often in its trials are Zelenectide pevedotin, Nivolumab and Nuzefatide pevedotin. The most-studied condition is Advanced Solid Tumor.

ClinicalTrials.gov trials by status

  • Recruiting114%
  • Active, closed686%

Trials by phase

  • Phase 2457%
  • Phase 1/2343%
01

Clinical trials sponsored by BicycleTx

7 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
NCT07450859 · ClinicalTrials.gov ↗ · Pancreatic Ductal Adenocarcinoma (PDAC)
Phase 2 Recruiting 2026-03 USA, South Korea
Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression
NCT05163041 · Advanced Solid Tumor
Drug: Nivolumab
Phase 1/2 Active, closed 2021-11 UK, USA
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
NCT04561362 · Urinary Bladder Neoplasm, Triple Negative Breast Neoplasms, Hormone Receptor Positive, HER2-negative Neoplasms
Phase 1/2 Active, closed 2020-07 UK, USA, France, Spain, Italy, Canada
Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)
NCT06225596 · ClinicalTrials.gov ↗ · Metastatic Urothelial Cancer
Phase 2 Active, closed 2024-01 UK, USA, China, Germany, France, Spain, Italy, Belgium, Poland, Turkey, Canada, Brazil, South Korea, Taiwan, Singapore, Australia, Israel
Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer
NCT06840483 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 2 Active, closed 2025-03 UK, USA, France, Spain, Italy, Belgium, Australia
Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression
NCT04180371 · ClinicalTrials.gov ↗ · Advanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer, Ovarian Cancer
Phase 1/2 Active, closed 2019-11 UK, USA, Spain, Belgium, South Korea
Zelenectide Pevedotin in NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer
NCT06933329 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 2 Active, closed 2025-07 France, Spain

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Drugs in BicycleTx trials

10 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

03

Conditions in BicycleTx trials

13 conditions
Advanced Solid Tumor1Urinary Bladder Neoplasm1Triple Negative Breast Neoplasms1Hormone Receptor Positive, HER2-negative Neoplasms1Hormone Receptor Positive, HER2-low Neoplasms1Breast Cancer1Metastatic Urothelial Cancer1Advanced Solid Tumor Historically Known for High EphA2 Expression1Urothelial Cancer1Ovarian Cancer1Non-small Cell Lung Cancer1Pancreatic Ductal Adenocarcinoma (PDAC)1Non-Small Cell Lung Cancer1
04

By trial register

RegisterTrialsRecruiting
Clinical trials in USA61
Clinical trials in UK50
Clinical trials in Spain50
Clinical trials in France40
Clinical trials in Italy30
Clinical trials in Belgium30
Clinical trials in South Korea31
Clinical trials in Canada20
Clinical trials in Australia20
Clinical trials in China10
Clinical trials in Germany10
Clinical trials in Poland10
Clinical trials in Turkey10
Clinical trials in Brazil10
Clinical trials in Taiwan10
Clinical trials in Singapore10
Clinical trials in Israel10

A trial with sites in more than one country appears in each of those registers.

05

Other sponsors in Advanced Solid Tumor

SponsorTrials
BeOne Medicines12
Daiichi Sankyo8
TORL Biotherapeutics5
OncoC45
LaNova Medicines5
MediLink Therapeutics (Suzhou)4
Suzhou Zelgen Biopharmaceuticals4
BioNTech3
EMD Serono Research & Development Institute3
GI Innovation3

Sponsors with the most current trials registered for this condition.

06

Questions about BicycleTx trials

How many clinical trials does BicycleTx sponsor?

BicycleTx is the lead sponsor of 7 current trials on ClinicalTrials.gov in our USA, UK, Spain, France, Italy, Belgium, South Korea, Canada, Australia, China, Germany, Poland, Turkey, Brazil, Taiwan, Singapore and Israel registers, as of the registry sync on 27 September 2026. Completed and withdrawn studies are not counted.

Are BicycleTx trials recruiting?

Yes. 1 of its 7 ClinicalTrials.gov trials is recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is BicycleTx testing?

Its current trials name 10 drugs and biologicals as interventions. The most frequent are Zelenectide pevedotin (4), Nivolumab (2), Nuzefatide pevedotin (2), Pembrolizumab (2) and Avelumab (1). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 27 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.