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Trackers› Clinical trials› Chronic Pain
Clinical trial register · United States · industry-sponsored

Chronic Pain Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9126 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 26 Sep 2026, 03:16 UTC
9126
Studies in scope
industry-sponsored, all four open statuses
4955
Recruiting now
open to new participants
2200
Lead sponsors
across recruiting studies
Top states
California 10 Arizona 8 Colorado 8 Florida 8 Illinois 5
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Recruitment status
Phase
Target enrolment
to

Chronic Pain trials in the USA

21 of 9126 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain
NCT07641504Chronic Pain, Low Back Pain
Eli Lilly and Company
Phase 2
150
Alabama, Arizona, California, Connecticut, Florida, Georgia, Illinois, Louisiana
2026-08-12
Recruiting
VETERANS AFFAIRS AUGUSTA
NCT07776600Chronic Pain
Companion IQ, Inc
Not applicable
200
Georgia
2026-08-01
Recruiting
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
NCT07641517Osteoarthritis, Knee, Chronic Pain
Eli Lilly and Company
Phase 2
150
Alabama, Arizona, California, Connecticut, Florida, Georgia, Illinois, Louisiana
2026-06-25
Recruiting
Post Market Evaluation of Real World Outcomes and Durability to Support Implantable Inceptivโ„ข Spinal Cord Stimulation Therapy
NCT07507422Chronic Pain, Intractable Pain
Medtronic
Observational
970
Arizona, California, Missouri, Texas
2026-04-17
By invitation
Examining the Impact of a Digital Health Program and TENS Device for Patients With Chronic Low Back Pain
NCT07011537Back Pain Lower Back Chronic, Chronic Pain, Musculoskeletal Pain
Hinge Health, Inc
Not applicable
196
Minnesota
2026-01-16
By invitation
Efficacy and Feasibility of BurstDR SCS in Painful Diabetic Neuropathy
NCT07250828Painful Diabetic Neuropathy (PDN), Diabetic Neuropathy, Neuropathic Pain, Chronic Pain
TriCity Research Center
Not applicable
20
Nebraska
2025-12-15
Recruiting
Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control
NCT07190807Chronic Pain, Intractable Pain, Low Back Pain, Chronic Low-back Pain
Boston Scientific Corporation
Not applicable
70
Colorado, Florida, Louisiana, New York, Pennsylvania, South Carolina, Texas
2025-11-07
Recruiting
Evaluating the Acceptability, Feasibility and Usability of Various Conversational Data Collection Software
NCT07336537Chronic Pain, Mental Health Disorders, Behavioral Health Challenges, Ecological Momentary Assessment Best Practices
AugMend Health Inc.
Not applicable
100
Massachusetts
2025-10-03
Not yet open
A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management
NCT05062902Interstitial Cystitis, Chronic Pain, Pelvic Floor; Relaxation, Pelvic Floor Disorders
HillMed Inc.
Phase EARLY_PHASE1
46
Texas
2025-09-15
Active, closed
Virtual Reality Treatment for Adults With Chronic Back Pain (VRNT)
NCT07033195Chronic Pain, Chronic Back Pain, Chronic Lower Back Pain (CLBP)
CognifiSense Inc.
Not applicable
200
Colorado
2025-06-01
Active, closed
Retrospective PNS Study
NCT06832449Chronic Pain
Curonix LLC
Observational
200
Colorado
2024-12-01
Recruiting
Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)
NCT06671132Chronic Pain, Low Back Pain
Evon Medics LLC
Phase 2
220
District of Columbia, Maryland
2024-10-23
Recruiting
Retrospective-Prospective PNS Study
NCT06845631Chronic Pain
Curonix LLC
Not applicable
40
Ohio
2024-07-01
Active, closed
Clinical Utility of Neurophysiological Measurements of ECAP-controlled Closed-loop SCS to Guide Treatment of Chronic Pain
NCT06229470Chronic Pain
Saluda Medical Pty Ltd
Not applicable
250
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa
2024-03-08
Recruiting
Pilot Study: Impact of Biomarker-Guided Dietary Supplementation on Quality-of-Life Measures in Subjects With Chronic Pain
NCT06247813Chronic Pain
Ethos Research & Development
Phase 2
75
Kentucky
2024-02-08
Active, closed
Clinical Study of a Micro-Implantable Pulse Generator for the Treatment of Peripheral Neuropathic Pain (COMFORT 2)
NCT05870124Peripheral Neuralgia, Peripheral Neuropathy, Chronic Pain
Nalu Medical, Inc.
Not applicable
185
Arizona, California, Colorado, District of Columbia, Florida, Kansas, Michigan, New Jersey
2023-04-27
Active, closed
HFIT Versus TENS Study for Chronic Low Back and Knee Pain
NCT05821530Chronic Pain, Knee Pain Chronic, Back Pain, Low
Hinge Health, Inc
Not applicable
325
California
2023-04-24
Active, closed
Clinical Study Of a Micro-Implantable Pulse Generator For The Treatment of Peripheral Neuropathic Pain
NCT05287373Peripheral Neuralgia, Chronic Pain
Nalu Medical, Inc.
Not applicable
89
Arizona, Arkansas, California, Colorado, District of Columbia, North Carolina, Oregon, Texas
2022-02-23
Active, closed
Paresthesia-Free Fast-Acting Subperception (FAST) Study
NCT04618471Chronic Pain
Boston Scientific Corporation
Not applicable
177
California, Colorado, Florida, Illinois, Indiana, Louisiana, New York, North Carolina
2021-02-10
Recruiting
Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator
NCT03876054Chronic Pain
Abbott Medical Devices
Observational
2,000
Arizona, California, Florida, Illinois, Indiana, Minnesota, Missouri, Nevada
2019-03-13
Recruiting
Patient Retrospective Outcomes (PRO)
NCT01550575Chronic Pain
Boston Scientific Corporation
Observational
15,000
Arizona, California, Colorado, Connecticut, Florida, Georgia, Hawaii, Idaho
2012-04-03
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 26 September 2026. https://priyalifescience.com/clinical-trials-usa/condition/chronic-pain

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,126 studies in total at the last sync on 26 Sep 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 21 of those studies listing the condition Chronic Pain.

How many Chronic Pain trials are recruiting in the US?

11 of the 21 studies on this page are recruiting new participants as of the 26 Sep 2026, 03:16 UTC sync. A further 1 have not yet opened recruitment, 7 are active but closed to new participants, and 2 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Chronic Pain), 21 studies
PhaseStudiesRecruitingShare
Not applicable12457.1%
Observational4319%
Phase 24419%
Phase EARLY_PHASE1104.8%

Most active sponsors

Lead sponsors with the most studies (Chronic Pain)
Lead sponsorStudiesRecruiting
Boston Scientific Corporation32
Curonix LLC21
Eli Lilly and Company22
Hinge Health, Inc20
Nalu Medical, Inc.20
Abbott Medical Devices11
AugMend Health Inc.11
CognifiSense Inc.10
Companion IQ, Inc11
Ethos Research & Development11

Top states

Top states (Chronic Pain), by number of studies with a site there
StateStudies
California10
Arizona8
Colorado8
Florida8
Georgia5
Illinois5
Louisiana4
Texas4
Connecticut3
District of Columbia3
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.