Impact of Intraoperative Perfusion Variability on Postoperative Troponin Elevation in Geriatric Patients Undergoing Major Oncologic Surgery

NCT07786753 · tracked via the Priya Life Science Turkey tracker

Sponsor

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Phase

Observational

Started

2026-09-01

Last updated

2026-09-16

Condition(s) studied

Postoperative Troponin ElevationIntraoperative Perfusion

Study summary

This prospective observational study aims to evaluate the association between intraoperative perfusion variability and postoperative troponin elevation in geriatric patients undergoing major oncologic surgery. Intraoperative hemodynamic and perfusion-related parameters will be recorded, and postoperative troponin levels will be assessed to investigate whether intraoperative perfusion changes are associated with myocardial injury. Troponin measurements will be obtained preoperatively and at 24 hours after surgery

Eligibility

Sex

ALL

Min age

65 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Age 65 years or older * Undergoing major abdominal oncologic surgery * Availability of preoperative and 24-hour postoperative troponin measurements * Complete intraoperative and postoperative patient monitoring records * Provision of written informed consent Exclusion Criteria: * Age younger than 65 years * Absence of preoperative or 24-hour postoperative troponin measurements * Incomplete intraoperative or postoperative patient monitoring records * Undergoing emergency surgery * Advanced heart failure * ASA Physical Status IV * Pulmonary artery pressure \>40 mmHg

Primary outcome measure(s)

Change in Serum Troponin Concentration From Preoperative Baseline to 24 Hours After Surgery — Preoperatively and 24 hours after surgery
Postoperative troponin elevation will be assessed by comparing serum troponin levels measured preoperatively and 24 hours after surgery. Its association with intraoperative perfusion variability will be evaluated.

Trial sites (1)

Facility	City	Region	Status
Ankara Dr. Abdurrahman Yurtaslan Oncolgy Training and Research Hospital	Yenimahalle	Ankara

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07786753 on ClinicalTrials.gov ↗ ← All trials in Turkey