Plasma I-FABP Measurement: Blood samples are collected and plasma I-FABP levels are measured to evaluate gastrointestinal involvement in pediatric IgA vasculitis.
Study summary
This prospective observational study aims to evaluate plasma intestinal fatty acid-binding protein (I-FABP) levels in children with IgA vasculitis and investigate their association with gastrointestinal involvement. Blood samples will be collected at diagnosis and during follow-up 2-4 weeks later. The study will assess the potential value of plasma I-FABP as a biomarker for gastrointestinal involvement in pediatric IgA vasculitis.
Eligibility
Sex
ALL
Min age
2 Years
Max age
18 Years
Healthy volunteers
No
Inclusion Criteria:
* Diagnosis of IgA vasculitis (Henoch-Schönlein purpura) according to EULAR/PRINTO/PRES classification criteria.
* Age between 2 and 18 years.
* Availability for blood sample collection at diagnosis (baseline visit).
* Ability to attend a routine follow-up visit approximately 2-4 weeks after diagnosis.
* Parent or legal guardian able and willing to provide written informed consent.
Exclusion Criteria:
* Refusal of informed consent by the parent/legal guardian.
* Inability to obtain a baseline blood sample.
* Inability to complete study follow-up procedures.
Primary outcome measure(s)
Plasma I-FABP Levels — At baseline (T0) and at follow-up 2-4 weeks after diagnosis Assessment of plasma I-FABP levels and their association with gastrointestinal involvement in pediatric IgA vasculitis patients.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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