Aerobic and resistance exercise: Because it was done on young girls who lead a sedentary lifestyle.
Study summary
Six-week exercise interventions in sedentary young women demonstrated that aerobic exercise and resistance exercise differentially optimize inflammatory and immune responses through their effects on osteocalcin and IgM, and IgA, respectively. These distinct effects of exercise modality on immune biomarkers can be utilized to design personalized exercise programs.
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
35 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* University students aged 18-30
* Individuals who have engaged in recreational exercise at least two days a week for the past three months
* Those with low or no smoking or alcohol consumption who volunteer to participate in the study.
Exclusion Criteria:
* Individuals who have had an infection or chronic illness in the last 6 months,
* Those with a history of autoimmune disease,
* Metabolic syndrome, or cardiovascular disease,
* Those who have used antibiotics or anti-inflammatory drugs in the last 3 months,
* Those who have suffered a serious injury during exercise or are unable to continue are not eligible.
Primary outcome measure(s)
Change in C-Reactive Protein (CRP) Levels — Baseline (Week 0) and Post-intervention (Week 6) Serum C-reactive protein levels will be measured using an ELISA kit to evaluate systemic inflammation. (Unit of measurement: mg/L)
Change in Interleukin-6 (IL-6) Levels — Baseline (Week 0) and Post-intervention (Week 6) Serum interleukin-6 levels will be analyzed to assess pro-inflammatory cytokine response. (Unit of measurement: pg/mL)
Change in Tumor Necrosis Factor-Alpha (TNF-α) Levels — Baseline (Week 0) and Post-intervention (Week 6) Serum tumor necrosis factor-alpha levels will be measured to evaluate pro-inflammatory cytokine activity. (Unit of measurement: pg/mL)
Change in Salivary Immunoglobulin A (IgA) Levels — Baseline (Week 0) and Post-intervention (Week 6) Salivary Immunoglobulin A levels will be measured to evaluate mucosal immune response. (Unit of measurement: mg/dL)
Change in Immunoglobulin M (IgM) Levels — Baseline (Week 0) and Post-intervention (Week 6) Serum Immunoglobulin M levels will be measured to assess acute infection and humoral immune response. (Unit of measurement: mg/dL)
Change in Immunoglobulin G (IgG) Levels — Baseline (Week 0) and Post-intervention (Week 6) Serum Immunoglobulin G levels will be measured to assess long-term immune memory and humoral immune response. (Unit of measurement: mg/dL)
Change in Leukocyte (WBC) Count — Baseline (Week 0) and Post-intervention (Week 6) Total leukocyte (White Blood Cell) count will be analyzed to assess general immune and inflammatory status. (Unit of measurement: cells/µL)
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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