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Clinical Trials in Turkey / NCT07577869
Recruiting Not applicable

Biceps Femoris Short Head (BiFeS) Block and Adductor Canal Block for Postoperative Analgesia Following Total Knee Arthroplasty

NCT07577869 · tracked via the Priya Life Science Turkey tracker
Sponsor
Ömer Kayar
Phase
Not applicable
Started
2026-06-02
Last updated
2026-06-12

Condition(s) studied

Postoperative Pain Following Knee ArthroplastyTotal Knee Arthroplasty

Investigational drug(s) / intervention(s)

Procedure: Biceps Femoris Short Head BlockProcedure: Spinal Anesthesia

Procedure: Biceps Femoris Short Head Block: Patients will receive spinal anesthesia followed by ultrasound-guided Biceps Femoris Short Head (BiFeS) block using 25 mL of 0.25% bupivacaine and adductor canal block using 15 mL of 0.25% bupivacaine before surgery. Standard multimodal analgesia will be provided using intravenous paracetamol and dexketoprofen, along with postoperative patient-controlled analgesia with morphine for 24 hours.

Procedure: Spinal Anesthesia: Patients will receive spinal anesthesia without peripheral nerve block. Standard multimodal analgesia will be provided using intravenous paracetamol and dexketoprofen, along with postoperative patient-controlled analgesia with morphine for 24 hours.

Study summary

This prospective randomized controlled study aims to evaluate the effect of ultrasound-guided Biceps Femoris Short Head (BiFeS) block combined with adductor canal block on postoperative opioid consumption and pain control in patients undergoing elective total knee arthroplasty under spinal anesthesia.

A total of 60 patients aged 18-80 years with ASA physical status I-III scheduled for unilateral elective total knee arthroplasty will be randomized into two groups. The intervention group will receive spinal anesthesia followed by BiFeS block and adductor canal block before surgery, in addition to standard multimodal analgesia and postoperative morphine patient-controlled analgesia (PCA). The control group will receive spinal anesthesia and standard multimodal analgesia with postoperative morphine PCA without peripheral nerve block.

The primary outcome is total morphine consumption during the first 24 postoperative hours. Secondary outcomes include postoperative pain scores assessed by Numeric Rating Scale (NRS), time to first analgesic requirement, time to first foot movement, and Quality of Recovery-15 (QoR-15) scores.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Patients aged 18 and older * ASA I-III * Patients scheduled for elective unilateral knee replacement * Eligibility for and consent to spinal anesthesia Exclusion Criteria: * History of allergy or anaphylaxis to local anesthetics, animal gelatin, or chlorhexidine * Bleeding diathesis/inability to discontinue anticoagulants * Infection (at the injection site/sepsis) * Neurological disorders or cognitive impairment affecting pain perception * Pregnancy, breastfeeding * Patients under 18 years of age

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Kayseri City Hospital Kayseri Kocasinan Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07577869 on ClinicalTrials.gov ↗ ← All trials in Turkey